LNPEP

  • Official Full Name

    leucyl/cystinyl aminopeptidase

  • Overview

    IRAP (also known as LNPEP) was originally described as an insulin-responsive aminopeptidase found in Glut4-containing vesicles. It is essentially always in the same compartments as Glut4 and has identical insulin-stimulated translocation patterns as Glut4 Aminopeptidase, Bacterial leucyl aminopeptidase, EC 3.4.11.10; Aeromonas proteolytica aminopeptidase; EC 3.4.11.1; EC 3.4.11.5; LAP; LAPEP; PEPS; Leucine aminopeptidase; Leucyl aminopeptidase; Peptidase S; Proline aminopeptidase; Prolyl aminopeptidase; leucine aminopeptidase 3; leucyl aminopeptidase; leucine aminopeptidase; leucyl peptidase; peptidase S; cytosol aminopeptidase; cathepsin III; L-leucine aminopeptidase; leucinaminopeptidase; leucinamide aminopeptidase; FTBL proteins; proteinates FTBL; aminopeptidase II; aminopeptidase III; aminopeptidase I.

  • Synonyms

    LNPEP;leucyl/cystinyl aminopeptidase;leucyl-cystinyl aminopeptidase;CAP;cystinyl aminopeptidase;P LAP;placental leucine aminopeptidase;PLAP;otase;oxytocinase;vasopressinase;AT (4) receptor;angiotensin IV receptor;insulin-regulated aminopeptid;Aeromonas Aminopeptidase;Aminopeptidase protein;Aminopeptidase;Bacterial leucyl aminopeptidase;EC 3.4.11.10;Aeromonas proteolytica aminopeptidase;EC 3.4.11.1;EC 3.4.11.5;LAP;LAPEP;PEPS;Leucine aminopeptidase;Leucyl aminopeptidase;Peptidase S;Proline aminopeptidase;Prolyl aminopeptidase;leucine aminopeptidase 3;leucyl peptidase;cytosol aminopeptidase;cathepsin III;L-leucine aminopeptidase;leucinaminopeptidase;leucinamide aminopeptidase;FTBL proteins;proteinates FTBL;aminopeptidase II;aminopeptidase III;aminopeptidase I

Recombinant Proteins

  • Human
  • Aeromonas
  • Zebrafish
  • Rat
  • Mouse
  • HEK293
  • Aeromonas Proteolytica
  • Mammalian Cell
  • E.coli
  • Mammalian cells
  • HEK293T
  • Myc&DDK
  • Non
  • His
  • His&Fc&Avi
  • Flag
Cat.# Product name Source (Host) Species Tag Protein Length Price
LNPEP-29H Recombinant Human LNPEP protein, MYC/DDK-tagged HEK293 Human Myc&DDK
Aminopeptidase-86A Recombinant Aeromonas Aminopeptidase Aeromonas Proteolytica Aeromonas Non
LNPEP-10022Z Recombinant Zebrafish LNPEP Mammalian Cell Zebrafish His
LNPEP-3430R Recombinant Rat LNPEP Protein Mammalian Cell Rat His
LNPEP-9167M Recombinant Mouse LNPEP Protein Mammalian Cell Mouse His
LNPEP-4705HCL Recombinant Human LNPEP 293 Cell Lysate HEK293 Human Non
Kit-1079 Aminopeptidase N (APN/CD13) Activity Assay Kit (Fluorometric) Non
LNPEP-12H Recombinant Human LNPEP Protein, His-tagged E.coli Human His Leu782~Leu1025
LNPEP-1309H Recombinant Human LNPEP Protein, His (Fc)-Avi-tagged HEK293 Human His&Fc&Avi
LNPEP-1309H-B Recombinant Human LNPEP Protein Pre-coupled Magnetic Beads HEK293 Human
LNPEP-306HFL Recombinant Full Length Human LNPEP Protein, C-Flag-tagged Mammalian cells Human Flag Full L.
LNPEP-3086R Recombinant Rat LNPEP Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
LNPEP-3086R-B Recombinant Rat LNPEP Protein Pre-coupled Magnetic Beads HEK293 Rat
LNPEP-3469H Recombinant Human LNPEP Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Human Myc&DDK
Lnpep-3805M Recombinant Mouse Lnpep Protein, Myc/DDK-tagged HEK293T Mouse Myc&DDK
LNPEP-5123M Recombinant Mouse LNPEP Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
LNPEP-5123M-B Recombinant Mouse LNPEP Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    LNPEP involved in several pathways and played different roles in them. We selected most pathways LNPEP participated on our site, such as Renin-angiotensin system, which may be useful for your reference. Also, other proteins which involved in the same pathway with LNPEP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Renin-angiotensin system ENPEP,ANPEP,ATP6AP2,MME,KLK1B9,Ren1,AGTR1A,CMA1,REN2,KLK1

    Protein Function

    LNPEP has several biochemical functions, for example, aminopeptidase activity,metalloaminopeptidase activity,metallopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by LNPEP itself. We selected most functions LNPEP had, and list some proteins which have the same functions with LNPEP. You can find most of the proteins on our site.

    Function Related Protein
    aminopeptidase activity ERAP2,CTSH,Npepo,METAP1D,METAP1,LAP3,TRHDE,RNPEP,METAP2,ERAP1
    zinc ion binding RNF44,LIMA1,MYRIP,RNF150,PHF1,CNBPA,USP39,EWSR1B,PHF7,SNCA
    peptide binding TPP1,AVPR1A,NPFFR2.1,CALR,NPFFR1L2,ADNP,CTSL2,FURIN,QRFPR,FNTB
    metalloaminopeptidase activity XPNPEP1,LTA4H,ANPEPB,ANPEPA,RNPEPL1,ENPEP,METAP2B,METAP2A,ERAP1,ERAP2
    protein binding S100A8,CBX8,COIL,NCBP2,PAGE5,MT3,CD97,FUT11,MDM2,MAPK3
    metallopeptidase activity Npepo,AGBL1,ADAM15,ADAMTS7,ADAM10,ADAM8A,ADAM23,AGBL4,MEP1A.2,NAALAD2

    Interacting Protein

    LNPEP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LNPEP here. Most of them are supplied by our site. Hope this information will be useful for your research of LNPEP.

    TCF4;REL;FATE1;TNKS2;argS;b3xyc5_sollc;cona_canen;Junb;CANX;HEATR3;TMEM263;GCC1;DROSHA;NDUFA13

    Resources

    Research Area

    Metalloproteases and Regulators

    References

    • Haralambieva, IH; Oberg, AL; et al. High-Dimensional Gene Expression Profiling Studies in High and Low Responders to Primary Smallpox Vaccination. JOURNAL OF INFECTIOUS DISEASES 206:1512-1520(2012).

    Reviews

    Write a review

    Q&As

    Ask a question

    Ask a Question for All LNPEP Products

    Required fields are marked with *

    My Review for All LNPEP Products

    Required fields are marked with *