LIPI
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Official Full Name
lipase, member I -
Overview
The protein encoded by this gene is a phospholipase that hydrolyzes phosphatidic acid to produce lysophosphatidic acid. The encoded protein, which can be inhibited by sodium vanadate, may be found exclusively in sperm. Defects in this gene are a cause of susceptibility to familial hypertrigliceridemia. -
Synonyms
LIPI;lipase, member I;lipase member I;cancer/testis antigen 17;CT17;LPDL;membrane associated phospholipase A1 beta;PRED5;LIPI_HUMAN;LPD lipase;Membrane-associated phosphatidic acid-selective phospholipase A1-beta;mPA-PLA1 beta;membrane-associated phospholipase A1 beta fl;membrane-associated phospholipase A1 beta 7B+;membrane-associated phospholipase A1 beta deltaE5;membrane-associated phospholipase A1 beta deltaE6.1;membrane-associated phospholipase A1 beta deltaE7.2;membrane-associated phospholipase A1 beta deltaE8-9
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| LIPI-989HCL | Recombinant Human LIPI cell lysate | Human | Non |
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| LIPI-2396H | Recombinant Human LIPI Protein, His-tagged | E.coli | Human | His | Met1-Phe334 |
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Involved Pathway
LIPI involved in several pathways and played different roles in them. We selected most pathways LIPI participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with LIPI were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
LIPI has several biochemical functions, for example, carboxylic ester hydrolase activity,heparin binding,phospholipase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by LIPI itself. We selected most functions LIPI had, and list some proteins which have the same functions with LIPI. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| heparin binding | ZFP207,SLIT1A,C6orf25,SELL,SERPINA5,VEGFAA,PTPRF,APOE,FGFR1,SLIT1B |
| carboxylic ester hydrolase activity | ACOT5,CES1C,ACOT10,CES1,ABHD2B,PNPLA7,BAAT,Ces2c,LIPCA,AADACL4 |
| phospholipase activity | PNPLA7,ABHD2B,Cel,LIPN,LIPC,NOTUM1A,PLA2G10,LIPH,CEL.1,PLA2G4AA |
Interacting Protein
LIPI has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LIPI here. Most of them are supplied by our site. Hope this information will be useful for your research of LIPI.
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References
- Atanackovic, D; Arfsten, J; et al. Cancer-testis antigens are commonly expressed in multiple myeloma and induce systemic immunity following allogeneic stem cell transplantation. BLOOD 109:1103-1112(2007).
