LIN37
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Official Full Name
lin-37 homolog (C. elegans) -
Overview
This gene encodes a protein expressed in the eye. -
Synonyms
LIN37;lin-37 homolog (C. elegans);protein lin-37 homolog;F25965;lin 37;ZK418.4;MGC9505;OTTMUSP00000032215;OTTMUSP00000032216;1810054G18Rik;Antolefinin;Antolefinine;Lin 37 homolog (C. elegans);LIN37_HUMAN;OTTMUSP00000032214;Protein F25965;Protein lin 37 homolog;RGD1308901;lin-37
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- GST
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| LIN37-1860H | Recombinant Human LIN37 protein, GST-tagged | E.coli | Human | GST | 1-93 aa | |
| LIN37-2654H | Recombinant Human LIN37 protein, His-tagged | E.coli | Human | His | 1-93 aa | |
| LIN37-1608H | Recombinant Human LIN37 | Mammalian Cell | Human | His |
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| LIN37-2609Z | Recombinant Zebrafish LIN37 | Mammalian Cell | Zebrafish | His |
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| LIN37-9114M | Recombinant Mouse LIN37 Protein | Mammalian Cell | Mouse | His |
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| LIN37-4732HCL | Recombinant Human LIN37 293 Cell Lysate | HEK293 | Human | Non |
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| LIN37-3366H | Recombinant Human LIN37 Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
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| LIN37-3366H-B | Recombinant Human LIN37 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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| LIN37-5091M | Recombinant Mouse LIN37 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| LIN37-5091M-B | Recombinant Mouse LIN37 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
LIN37 involved in several pathways and played different roles in them. We selected most pathways LIN37 participated on our site, such as Cell Cycle,Cell Cycle, Mitotic,G0 and Early G1, which may be useful for your reference. Also, other proteins which involved in the same pathway with LIN37 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Mitotic G1-G1/S phases | LIN9,MYCA,MYBL2,LIN52,LIN54,TOP2A,DYRK1A |
| Cell Cycle, Mitotic | E2F2,SSNA1,GINS1,DPF1,MLF1IP,CENPN,NSL1,CENPK,PANE1,TUBGCP5 |
| Polo-like kinase mediated events | LIN9,LIN52,FOXM1 |
| G0 and Early G1 | LIN54,LIN52,DYRK1A,PIANP,MYBL2,TOP2A,LIN9,E2F4 |
| Cell cycle | ANAPC1,POLD3,CDKN2A,MCM5,SYCP2,ERCC6L,MAPRE1A,RBL1,NIPBL,BARD1 |
| Mitotic G2-G2/M phases | CDK11A,TCTN2,TUBGCP3,LIN9,CDK11B,TUBGCP4,TUBGCP5,TUBGCP2,TUBG2,BORA |
| G2/M Transition | ACTR1A,CLASP1,LIN9,DCTN2,PCM1,ODF2B,CEP152,ODF2,CLASP1A,SDCCAG8 |
Protein Function
LIN37 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LIN37 itself. We selected most functions LIN37 had, and list some proteins which have the same functions with LIN37. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | AACS,TMSB10,RPLP2,TAL2,TBX1,TTC19,SPDL1,BUB3,PPP4R4,UBL4B |
Interacting Protein
LIN37 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LIN37 here. Most of them are supplied by our site. Hope this information will be useful for your research of LIN37.
RBL2;MAGEA6;CDR2;KRT31
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References
- Sandoval, R; Pilkinton, M; et al. Deletion of the p107/p130-binding domain of Mip130/LIN-9 bypasses the requirement for CDK4 activity for the dissociation of Mip130/LIN-9 from p107/p130-E2F4 complex. EXPERIMENTAL CELL RESEARCH 315:2914-2920(2009).
- Litovchick, L; Sadasivam, S; et al. Evolutionarily conserved multisubunit RBL2/p130 and E2F4 protein complex represses human cell cycle-dependent genes in quiescence. MOLECULAR CELL 26:539-551(2007).
