LHX5
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Official Full Name
LIM homeobox 5 -
Overview
This gene encodes a protein belonging to a large protein family, members of which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator and be involved in the control of differentiation and development of the forebrain. In mice, this protein is essential for the regulation of precursor cell proliferation and the control of neuronal differentiation and migration during hippocampal development. This protein is involved in learning and motor functions in adult mice. -
Synonyms
LHX5;LIM homeobox 5;LIM/homeobox protein Lhx5;LHX 5;LHX5_HUMAN;LIM homeobox protein 5;MGC129689
Recombinant Proteins
- Human
- Rat
- Zebrafish
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- GST
- His
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| LHX5-572H | Recombinant Human LHX5, GST-tagged | E.coli | Human | GST | 260-402aa |
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| LHX5-3405R | Recombinant Rat LHX5 Protein | Mammalian Cell | Rat | His |
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| LHX5-8819Z | Recombinant Zebrafish LHX5 | Mammalian Cell | Zebrafish | His |
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| LHX5-9089M | Recombinant Mouse LHX5 Protein | Mammalian Cell | Mouse | His |
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| LHX5-3061R | Recombinant Rat LHX5 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| LHX5-3061R-B | Recombinant Rat LHX5 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| LHX5-5075M | Recombinant Mouse LHX5 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| LHX5-5075M-B | Recombinant Mouse LHX5 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
LHX5 involved in several pathways and played different roles in them. We selected most pathways LHX5 participated on our site, such as Signaling pathways regulating pluripotency of stem cells, which may be useful for your reference. Also, other proteins which involved in the same pathway with LHX5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Signaling pathways regulating pluripotency of stem cells | BMI1,FZD2,WNT2B,BMP4,WNT9B,ESX1,AKT1,HAND1,RAF1,WNT3 |
Protein Function
LHX5 has several biochemical functions, for example, sequence-specific DNA binding,zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LHX5 itself. We selected most functions LHX5 had, and list some proteins which have the same functions with LHX5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| zinc ion binding | ZFP259,DTNBA,PIAS4,LIN28A,ING1,CXXC5,ZRANB1,DNAJC21,KDM4A,C6AST1 |
| sequence-specific DNA binding | POU3F1,HOXC12B,NKX3,HOXC6A,HOXC12A,MAFF,JUNBB,FOXO1,RORA,TFCP2 |
Interacting Protein
LHX5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LHX5 here. Most of them are supplied by our site. Hope this information will be useful for your research of LHX5.
Resources
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References
- Mastick, GS; Andrews, GL; et al. Pax6 regulates the identity of embryonic diencephalic neurons. MOLECULAR AND CELLULAR NEUROSCIENCE 17:190-207(2001).
