LHX2
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Official Full Name
LIM homeobox 2 -
Overview
This gene encodes a protein belonging to a large protein family, members of which carry the LIM domain, a unique;cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator. The protein can;recapitulate or rescue phenotypes in Drosophila caused by a related protein, suggesting conservation of function;during evolution. -
Synonyms
LHX2;LIM homeobox 2;LIM/homeobox protein Lhx2;hLhx2;LH 2;Homeobox protein LH2;Human LIM homeobox domain protein (hLH 2) mRNA complete cds;LH2;LIM HOX gene 2;LIM protein Lhx2;OTTHUMP00000022092;OTTHUMP00000022093;homeobox protein LH-2;LIM homeobox protein 2
Recombinant Proteins
- Human
- Rhesus macaque
- Chicken
- E.coli
- Mammalian Cell
- HEK293
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| LHX2-569H | Recombinant Human LHX2, His-tagged | E.coli | Human | His | 1-396aa | |
| LHX2-2509R | Recombinant Rhesus monkey LHX2 Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| LHX2-45H | Recombinant Human LHX2 protein, His-tagged | E.coli | Human | His |
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| LHX2-6452C | Recombinant Chicken LHX2 | Mammalian Cell | Chicken | His |
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| LHX2-660H | Recombinant Human LHX2 | Mammalian Cell | Human | His |
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| LHX2-4751HCL | Recombinant Human LHX2 293 Cell Lysate | HEK293 | Human | Non |
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| LHX2-2330R | Recombinant Rhesus Macaque LHX2 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| LHX2-2330R-B | Recombinant Rhesus Macaque LHX2 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| LHX2-3356H | Recombinant Human LHX2 Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
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| LHX2-3356H-B | Recombinant Human LHX2 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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Involved Pathway
LHX2 involved in several pathways and played different roles in them. We selected most pathways LHX2 participated on our site, such as Neural Crest Differentiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with LHX2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Neural Crest Differentiation | GBX2,CTBP2,TXLNB,TBX6,TFAP2A,SOX10,OLIG2,SOX5,PHOX2B,PMP22 |
Protein Function
LHX2 has several biochemical functions, for example, chromatin binding,sequence-specific DNA binding,transcription factor activity, RNA polymerase II transcription factor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LHX2 itself. We selected most functions LHX2 had, and list some proteins which have the same functions with LHX2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transcription factor activity, RNA polymerase II transcription factor binding | SRF,GATA4,TWIST2,NACC2,THRAA,MYOCD,YAP1,MAMSTR,ATF4,ZNF296 |
| sequence-specific DNA binding | CEBP1,HOXB4A,FOXH1,HOXA9B,HOXC9,NFYBA,CTCF,ELK4,RXRAA,FOXL2 |
| zinc ion binding | PJA2,RNF148,ANPEPB,RNF6,HHIP,MUL1,SIRT6,GTF2H2C,VPS41,SQSTM1 |
| chromatin binding | SKOR2,NPM2,HMGXB4A,PHC1,HMGB3B,JUB,PRKCBB,DLX2,KLF14,GATA3 |
Interacting Protein
LHX2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LHX2 here. Most of them are supplied by our site. Hope this information will be useful for your research of LHX2.
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