LCN12
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Official Full Name
lipocalin 12 -
Overview
Members of the lipocalin family, such as LCN12, have a common structure consisting of an 8-stranded antiparallel;beta-barrel that forms a cup-shaped ligand-binding pocket or calyx. Lipocalins generally bind small hydrophobic;ligands and transport them to specific cells (Suzuki et al., 2004 (PubMed 15363845)). -
Synonyms
LCN12;lipocalin 12;epididymal-specific lipocalin-12;MGC48935;Lipocalcin 12;MGC34753
Recombinant Proteins
- Human
- Mouse
- Rat
- Rhesus macaque
- E.coli
- Mammalian Cell
- HEK293
- His&GST
- His
- Non
- His&Fc&Avi
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| LCN12-500H | Recombinant Human LCN12 Protein, His/GST-tagged | E.coli | Human | His&GST | Leu61~Gly184 | |
| Lcn12-501M | Recombinant Mouse Lcn12 Protein, His/GST-tagged | E.coli | Mouse | His&GST | Gln30~Cys193 | |
| Lcn12-502R | Recombinant Rat Lcn12 Protein, His/GST-tagged | E.coli | Rat | His&GST | Ser21~Arg109+Gly151~Asp182 | |
| LCN12-2477R | Recombinant Rhesus monkey LCN12 Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| LCN12-975HCL | Recombinant Human LCN12 cell lysate | Human | Non |
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| LCN12-2298R | Recombinant Rhesus Macaque LCN12 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| LCN12-2298R-B | Recombinant Rhesus Macaque LCN12 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| LCN12-301442H | Recombinant Human LCN12 protein, GST-tagged | E.coli | Human | GST | Asn406-Ile532 |
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| LCN12-4212H | Recombinant Human LCN12 Protein (Leu61-Gly184), N-GST tagged | E.coli | Human | GST | Leu61-Gly184 |
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Involved Pathway
LCN12 involved in several pathways and played different roles in them. We selected most pathways LCN12 participated on our site, such as SLC-mediated transmembrane transport,Transmembrane transport of small molecules,Transport of fatty acids, which may be useful for your reference. Also, other proteins which involved in the same pathway with LCN12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Transport of vitamins, nucleosides, and related molecules | SLC29A3,SLC35A3,SLC5A6A,SLCO2A1,SLCO3A1,LCN9,SLC35A3B,SLC29A2,SLC35B4,SLC28A3 |
| Transmembrane transport of small molecules | SLC9A7,CLCNK,SLC13A5,ABCA7,SLC6A1B,SLC35B4,SLC20A1A,RHCG2A,SLC35A2,SLC26A7 |
| SLC-mediated transmembrane transport | SLC6A1A,SLC43A2,SLC30A2,SLC13A2,SLC29A2,LCN1,SLC7A3A,SLC14A1,SLC39A6,SLC6A2 |
| Transport of fatty acids | LCN15,SLC27A4,APOD,LCN1,LCN9 |
Protein Function
LCN12 has several biochemical functions, for example, retinoic acid binding,transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by LCN12 itself. We selected most functions LCN12 had, and list some proteins which have the same functions with LCN12. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| retinoic acid binding | UGT1A3,UGT1A1,UGT1A2,RARA,LRAT,CRABP1,CYP26B1,CRABP2,CRABP2B,PTGDSB |
| transporter activity | SYPL2A,UCP3,SLC22A17,CLVS2,SLC26A3,APODB,CSN1S1,ATP5B,VPS9D1,SLC5A10 |
Interacting Protein
LCN12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LCN12 here. Most of them are supplied by our site. Hope this information will be useful for your research of LCN12.
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References
- Cheng, L; Xing, H; et al. Lipocalin-2 Promotes M1 Macrophages Polarization in a Mouse Cardiac Ischaemia-Reperfusion Injury Model. SCANDINAVIAN JOURNAL OF IMMUNOLOGY 81:31-38(2015).
- Ginde, AA; Blatchford, PJ; et al. AGE-RELATED DIFFERENCES IN BIOMARKERS OF ACUTE INFLAMMATION DURING HOSPITALIZATION FOR SEPSIS. SHOCK 42:99-107(2014).
