LCE1A
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Official Full Name
late cornified envelope 1A -
Overview
LCE1A belongs to the late cornified envelope (LCE) gene cluster within the epidermal differentiation complex (EDC) on;chromosome 1. The LCE cluster contains multiple conserved genes that encode stratum corneum proteins, and these genes;are expressed relatively late during fetal assembly of the skin cornified envelope (Jackson et al., 2005 (PubMed;15854049)). For further information on the LCE gene cluster, see GENE FAMILY below. -
Synonyms
LCE1A;late cornified envelope 1A;late cornified envelope protein 1A;LEP1;Late envelope protein 1;LCE1A_HUMAN
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Involved Pathway
LCE1A involved in several pathways and played different roles in them. We selected most pathways LCE1A participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with LCE1A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
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Protein Function
LCE1A has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by LCE1A itself. We selected most functions LCE1A had, and list some proteins which have the same functions with LCE1A. You can find most of the proteins on our site.
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Interacting Protein
LCE1A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LCE1A here. Most of them are supplied by our site. Hope this information will be useful for your research of LCE1A.
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References
- Clements, SE; Techanukul, T; et al. Mutations in AEC syndrome skin reveal a role for p63 in basement membrane adhesion, skin barrier integrity and hair follicle biology. BRITISH JOURNAL OF DERMATOLOGY 167:134-144(2012).
- Tong, L; Corrales, RM; et al. Expression and regulation of cornified envelope proteins in human corneal epithelium. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 47:1938-1946(2006).
