LAX1
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Official Full Name
lymphocyte transmembrane adaptor 1 -
Synonyms
LAX1;lymphocyte transmembrane adaptor 1;lymphocyte transmembrane adapter 1;FLJ20340;LAT like membrane associated protein;LAX;linker for activation of x cells;Membrane associated adapter protein LAX;OTTHUMP00000034094;LAT-like membrane associated protein;membrane-associated adapter protein LAX
Recombinant Proteins
- Human
- Rat
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| LAX1-3642H | Recombinant Human LAX1 protein, His-tagged | E.coli | Human | His | 77-398 aa | |
| LAX1-3361R | Recombinant Rat LAX1 Protein | Mammalian Cell | Rat | His |
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| LAX1-8972M | Recombinant Mouse LAX1 Protein | Mammalian Cell | Mouse | His |
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| LAX1-4812HCL | Recombinant Human LAX1 293 Cell Lysate | HEK293 | Human | Non |
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| LAX1-3017R | Recombinant Rat LAX1 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| LAX1-3017R-B | Recombinant Rat LAX1 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| LAX1-5004M | Recombinant Mouse LAX1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| LAX1-5004M-B | Recombinant Mouse LAX1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
LAX1 involved in several pathways and played different roles in them. We selected most pathways LAX1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with LAX1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
LAX1 has several biochemical functions, for example, SH2 domain binding,protein binding,protein kinase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LAX1 itself. We selected most functions LAX1 had, and list some proteins which have the same functions with LAX1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| SH2 domain binding | NLK,AFAP1L2,NUP62,SQSTM1,SIT1,TRPV4,GNB2L1,DLC1,SH3PXD2B,ARHGAP5 |
| protein kinase binding | TPRKB,TRIM5,RACGAP1,PRKAG1,XBP1,ACVRL1,EPHA1,FAF1,CNPPD1,ELP2 |
| protein binding | MAGI2,LIMK2,FBXO11,FOXN3,TAG-260,DNAAF2,DAPK2,UPF3B,BCL2,BTC |
Interacting Protein
LAX1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LAX1 here. Most of them are supplied by our site. Hope this information will be useful for your research of LAX1.
GRB7;STAMBPL1;RAB8A;CTLA4;TRIM25
Resources
Research Area
Phospholipases, Small GTPases, and Other Molecules in the Akt PathwayT Cell Antigen Recognition
B Cell Receptor-Associated Proteins
Related Services
Related Products
References
- Arndt, B; Kalinski, T; et al. Cooperative immunoregulatory function of the transmembrane adaptor proteins SIT and LAX. JOURNAL OF LEUKOCYTE BIOLOGY 93:353-362(2013).
- Liu, Y; Zhang, WG; et al. Identification of a new transmembrane adaptor protein that constitutively binds Grb2 in B cells. JOURNAL OF LEUKOCYTE BIOLOGY 84:842-851(2008).
- Engelke, M; Engels, N; et al. Ca2+ signaling in antigen receptor-activated B lymphocytes. IMMUNOLOGICAL REVIEWS 218:235-246(2007).
- Hubener, C; Mincheva, A; et al. Complete sequence, genomic organization, and chromosomal localization of the human gene encoding the SHP2-interacting transmembrane adaptor protein (SIT). IMMUNOGENETICS 53:337-341(2001).
