LAPTM4B
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Official Full Name
lysosomal-associated protein transmembrane 4B -
Synonyms
LAPTM4beta;C330023P13Rik
Recombinant Proteins
- Human
- Zebrafish
- Rat
- Mouse
- Mus musculus
- Macaca fascicularis
- Bovine
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- E.coli expression system
- His
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
LAPTM4B involved in several pathways and played different roles in them. We selected most pathways LAPTM4B participated on our site, such as Lysosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with LAPTM4B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Lysosome | GNSB,AGA,LAPTM5,GALNS,AP3B2,ENTPD4,GLB1,SORT1A,GNS,ASAH1B |
Protein Function
LAPTM4B has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LAPTM4B itself. We selected most functions LAPTM4B had, and list some proteins which have the same functions with LAPTM4B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | CDCA5,ZBTB24,RXRB,ASPA,MAGEA6,CIB3,SENP5,TRAF7,CHMP5,RELA |
Interacting Protein
LAPTM4B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LAPTM4B here. Most of them are supplied by our site. Hope this information will be useful for your research of LAPTM4B.
EGFR;NAALADL2;EXOC4;MET;FGFR2
Resources
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References
- Tan, XJ; Sun, Y; et al. LAPTM4B is a PtdIns(4,5)P-2 effector that regulates EGFR signaling, lysosomal sorting, and degradation. EMBO JOURNAL 34:475-490(2015).
- Tan, XJ; Thapa, N; et al. A Kinase-Independent Role for EGF Receptor in Autophagy Initiation. CELL 160:145-160(2015).
