KRT13
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Official Full Name
keratin 13 -
Overview
The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in this gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus. The type I cytokeratins are clustered in a region of chromosome 17q21.2. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been described. The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with kerat -
Synonyms
KRT13;keratin 13;keratin, type I cytoskeletal 13;CK13;cytokeratin 13;K13;keratin;type I cytoskeletal 13;MGC3781;MGC161462;CK-13;keratin-13;cytokeratin-13
Recombinant Proteins
- Human
- Rat
- E.coli
- Mammalian Cell
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His&T7
- His
- Non
- His&SUMO
- His&Fc&Avi
- GST
- N-His&C-Myc
Involved Pathway
KRT13 involved in several pathways and played different roles in them. We selected most pathways KRT13 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with KRT13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
KRT13 has several biochemical functions, for example, structural molecule activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KRT13 itself. We selected most functions KRT13 had, and list some proteins which have the same functions with KRT13. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| structural molecule activity | CLDN15A,KRT75,COPB1,JUP,CLDNC,IVL,RLN3B,KRT33A,CLDNB,CLDNK |
Interacting Protein
KRT13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KRT13 here. Most of them are supplied by our site. Hope this information will be useful for your research of KRT13.
APC;midostaurin;GABARAP;ALB;ESR1;GABARAPL2;MAP1LC3B;GABARAPL1;MAP1LC3A
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