KRIT1
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Official Full Name
KRIT1, ankyrin repeat containing
Recombinant Proteins
- Human
- Rhesus macaque
- Chicken
- Mouse
- Zebrafish
- E.coli
- Mammalian Cell
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- His&Fc&Avi
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| KRIT1-2773H | Recombinant Human KRIT1 protein, His-tagged | E.coli | Human | His | 471-585 aa | |
| KRIT1-2444R | Recombinant Rhesus monkey KRIT1 Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| KRIT1-2660C | Recombinant Chicken KRIT1 | Mammalian Cell | Chicken | His |
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| KRIT1-8811M | Recombinant Mouse KRIT1 Protein | Mammalian Cell | Mouse | His |
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| KRIT1-9975Z | Recombinant Zebrafish KRIT1 | Mammalian Cell | Zebrafish | His |
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| KRIT1-2265R | Recombinant Rhesus Macaque KRIT1 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| KRIT1-2265R-B | Recombinant Rhesus Macaque KRIT1 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| KRIT1-4879H | Recombinant Human KRIT1 Protein, GST-tagged | Wheat Germ | Human | GST |
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| KRIT1-4908M | Recombinant Mouse KRIT1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| KRIT1-4908M-B | Recombinant Mouse KRIT1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| KRIT1-5917HF | Recombinant Full Length Human KRIT1 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 736 amino acids |
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Involved Pathway
KRIT1 involved in several pathways and played different roles in them. We selected most pathways KRIT1 participated on our site, such as Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with KRIT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Rap signaling pathway | PARD3,KITLG,LPAR2,FGF10,FLT4,MAP2K1,F2R,RAC1,RASSF5,ITGAM |
Protein Function
KRIT1 has several biochemical functions, for example, GTPase regulator activity,microtubule binding,phosphatidylinositol-4,5-bisphosphate binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KRIT1 itself. We selected most functions KRIT1 had, and list some proteins which have the same functions with KRIT1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| GTPase regulator activity | PCP2,RHPN1,RGS12B,WAS,GPSM2,GPSM1B,ARL2BP,WASL,GPSM3,RGS14A |
| microtubule binding | MTAP7D3,BIRC5,MAP1LC3C,CLASP1,CCDC87,GAS2L2,KIF26A,CENPE,KIF5AA,KATNAL1 |
| protein complex binding | RIPK1,LRP1,KRAS,STK11,CASP8,ARRB2,NFYB,C8G,KIF11,TAB1 |
| phosphatidylinositol-4,5-bisphosphate binding | PHLDA3,LDLRAP1,FAM123A,SNX20,EXOC1,FCHO2,FRMPD4,ASAP1,TULP1,ACTN2 |
| protein binding | TXNDC5,PARP9,C1orf51,MAPT,NRSN1,MT1A,PRH2,FBXW11,EIF4E2,CDT1 |
Interacting Protein
KRIT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KRIT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of KRIT1.
Resources
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References
- Shi, CB; Shenkar, R; et al. Immune complex formation and in situ B-cell clonal expansion in human cerebral cavernous malformations. JOURNAL OF NEUROIMMUNOLOGY 272:67-75(2014).
- Grippaudo, FR; Piane, M; et al. Cutaneous Venous Malformations Related to KRIT1 Mutation: Case Report and Literature Review. JOURNAL OF MOLECULAR NEUROSCIENCE 51:442-445(2013).
