KLRA2
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Official Full Name
killer cell lectin-like receptor, subfamily A, member 2 -
Overview
The gene is a member of the large lectin-like type 2 transmembrane receptor family of the natural killer gene complex. The gene is located distantly telomeric to its familys gene cluster on chromosome 6. The gene differs from the other genes in its cluster as its promoter region contains long and short interspersed repetitive elements suggesting a possible rearrangement or gene conversion. It is unknown whether this genes encoded protein is involved with natural killer cell differentiation as are its other family members. Alternative splicing results in multiple transcript variants. -
Synonyms
KLRA2;killer cell lectin-like receptor, subfamily A, member 2;killer cell lectin-like receptor 2;Ly49-b;Ly-49b;Ly49b;Lymphocyte antigen 49b;T-cell surface glycoprotein Ly-49B;membrane protein Ly49b;NK cell inhibitory receptor Klra2;T-cell surface glycoprotein Ly49b;killer cell lectin-like receptor subfamily A member 30;Klra30
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Involved Pathway
KLRA2 involved in several pathways and played different roles in them. We selected most pathways KLRA2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with KLRA2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
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Protein Function
KLRA2 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by KLRA2 itself. We selected most functions KLRA2 had, and list some proteins which have the same functions with KLRA2. You can find most of the proteins on our site.
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Interacting Protein
KLRA2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KLRA2 here. Most of them are supplied by our site. Hope this information will be useful for your research of KLRA2.
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References
- Birkhauser, FD; Koya, RC; et al. Dendritic Cell-Based Immunotherapy in Prevention and Treatment of Renal Cell Carcinoma: Efficacy, Safety, and Activity of Ad-GM.CAIX in Immunocompetent Mouse Models. JOURNAL OF IMMUNOTHERAPY 36:102-111(2013).
