KLK13
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Official Full Name
kallikrein-related peptidase 13 -
Overview
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Expression of this gene is regulated by steroid hormones and may be useful as a marker for breast cancer. An additional transcript variant has been identified, but its full length sequence has not been determined. [provided by RefSeq, Jul 2008] -
Synonyms
KLK13;kallikrein-related peptidase 13;KLKL4;KLK-L4;kallikrein-13;kallikrein 13;kallikrein-like gene 4;kallikrein-like protein 4
Recombinant Proteins
- Human
- Mouse
- Human Cell
- HEK293
- Insect Cell
- E.coli
- Mammalian cells
- Non
- His
- His&T7
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| KLK13-301H | Recombinant Human KLK13, None tagged | Human Cell | Human | Non | 1-262 a.a. |
|
| KLK13-302H | Active Recombinant Human KLK13 protein(Met1-Ile262), His-tagged | HEK293 | Human | His | Met1-Ile262 |
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| KLK13-31H | Recombinant Human KLK13 protein, His-tagged | Insect Cell | Human | His |
|
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| KLK13-7999H | Recombinant Human KLK13 protein, His & T7-tagged | E.coli | Human | His&T7 | Glu22~Gln277 |
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| Klk13-8000M | Recombinant Mouse Klk13 protein, His & T7-tagged | E.coli | Mouse | His&T7 | Val25~Ala261 |
|
| KLK13-2899HCL | Recombinant Human KLK13 cell lysate | Human Cell | Human | Non |
|
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| KLK13-2900HCL | Recombinant Human KLK13 cell lysate | Human Cell | Human | Non |
|
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| KLK13-076H | Recombinant Human KLK13 Protein, His-tagged | HEK293 | Human | His | 277 |
|
| KLK13-3524H | Recombinant Human KLK13 Protein (Gly17-Ile262), C-His tagged | Mammalian cells | Human | His | Gly17-Ile262 |
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Involved Pathway
KLK13 involved in several pathways and played different roles in them. We selected most pathways KLK13 participated on our site, such as Metabolism of proteins,Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs), which may be useful for your reference. Also, other proteins which involved in the same pathway with KLK13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | IGFBP5,IGFBP6A,IGFBP1A,IGFBP1B,IGF2B,IGFBP5A,IGFBP2B,IGFBP4,IGFBP6,PAPPAB |
| Metabolism of proteins | TIMM21,PPP6R3,ST8SIA2,DPH3,CPB2,EEF1B2,KCNA3,ADAMTSL4,TUBA1B,CST3 |
Protein Function
KLK13 has several biochemical functions, for example, hydrolase activity,protein binding,serine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KLK13 itself. We selected most functions KLK13 had, and list some proteins which have the same functions with KLK13. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| serine-type endopeptidase activity | PROCA,KLK6,PRSS58,IMMP2L,KLK1B8,TMPRSS2,KEX2,TPSAB1,F9B,PRSS8 |
| hydrolase activity | PTPN2B,CTSM,LIPN,TMPRSS4A,ZRANB3,PSMA6B,REXO1,PXYLP1,CTDNEP1A,ALP3 |
| protein binding | XRN1,TMEM66,PROP1,MPZL1L,AHSA1,MAPKBP1,KLRG1,SEC61G,RBMY1F,PITPNM1 |
Interacting Protein
KLK13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KLK13 here. Most of them are supplied by our site. Hope this information will be useful for your research of KLK13.
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