KLHL4
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Official Full Name
kelch-like 4 (Drosophila) -
Overview
This gene encodes a member of the kelch family of proteins, which are characterized by kelch repeat motifs and a POZ/BTB protein-binding domain. It is thought that kelch repeats are actin binding domains. However, the specific function of this protein has not been determined. Alternative splicing of this gene results in two transcript variants encoding different isoforms. -
Synonyms
KLHL4;kelch-like 4 (Drosophila);kelch (Drosophila) like 4;kelch-like protein 4;DKELCHL;KHL4;KIAA1687;KLHL4_HUMAN;OTTHUMP00000023632;OTTHUMP00000023633
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| KLHL4-429H | Recombinant Human KLHL4, GST-tagged | E.coli | Human | GST | 15-164aa | |
| KLHL4-6178Z | Recombinant Zebrafish KLHL4 | Mammalian Cell | Zebrafish | His |
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| KLHL4-944HCL | Recombinant Human KLHL4 cell lysate | Human | Non |
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Involved Pathway
KLHL4 involved in several pathways and played different roles in them. We selected most pathways KLHL4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with KLHL4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
KLHL4 has several biochemical functions, for example, actin binding,molecular_function,contributes_to ubiquitin-protein transferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KLHL4 itself. We selected most functions KLHL4 had, and list some proteins which have the same functions with KLHL4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| molecular_function | HSD17B13,RPL41,GM1987,OBSL1,VSG1,TMEM20,TMEM9,FBXO40,UBL7A,Ajap1 |
| contributes_to ubiquitin-protein transferase activity | ANAPC11,TCEB1,KLHL17,KLHL24B,KLHL30,ERCC8,BCOR,BARD1,KLHL5,RNF40 |
| actin binding | HIP1R,SPTBN2,PFN3,BAIAP2L1,GCSAM,FGD4,CALD1B,SMTN,SNTB2,KLHL1 |
Interacting Protein
KLHL4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KLHL4 here. Most of them are supplied by our site. Hope this information will be useful for your research of KLHL4.
NUDCD3;NUDCD2
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References
- Aromolaran, KA; Benzow, KA; et al. The Kelch-like protein 1 modulates P/Q-type calcium current density. NEUROSCIENCE 145:841-850(2007).
