KLF13
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Official Full Name
Kruppel-like factor 13 -
Overview
KLF13 belongs to a family of transcription factors that contain 3 classical zinc finger DNA-binding domains consisting;of a zinc atom tetrahedrally coordinated by 2 cysteines and 2 histidines (C2H2 motif). These transcription factors;bind to GC-rich sequences and related GT and CACCC boxes (Scohy et al., 2000 (PubMed 11087666)). -
Synonyms
KLF13;Kruppel-like factor 13;Krueppel-like factor 13;BTEB3;FKLF 2;NSLP1;RFLAT 1;BTE-binding protein 3;transcription factor BTEB3;transcription factor NSLP1;Sp1 like zinc finger transcription factor;basic transcription element binding protein 3
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- His
- His&GST
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| KLF13-397H | Recombinant Human KLF13, His-tagged | E.coli | Human | His | 1-288aa |
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| KLF13-4597Z | Recombinant Zebrafish KLF13 | Mammalian Cell | Zebrafish | His |
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| KLF13-507H | Recombinant Human KLF13 Protein, GST-His-tagged | E.coli | Human | His&GST |
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| KLF13-8677M | Recombinant Mouse KLF13 Protein | Mammalian Cell | Mouse | His |
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| KLF13-4931HCL | Recombinant Human KLF13 293 Cell Lysate | HEK293 | Human | Non |
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| KLF13-4836M | Recombinant Mouse KLF13 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| KLF13-4836M-B | Recombinant Mouse KLF13 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
KLF13 involved in several pathways and played different roles in them. We selected most pathways KLF13 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with KLF13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
KLF13 has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding,metal ion binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KLF13 itself. We selected most functions KLF13 had, and list some proteins which have the same functions with KLF13. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| RNA polymerase II core promoter proximal region sequence-specific DNA binding | TFAP2A,RFX8,MAFB,ZNF718,ZNF92,RFX1,PBX1,SFPI1,SOX10,ASCL2 |
| protein binding | MEF2D,USH1C,DKC1,HNRNPH1,FAM20A,COL13A1,KNDC1,CRHR2,PRLR,CCDC70 |
| metal ion binding | ZNF32,STK32C,ARFGAP2,GTPBP6,ZBTB37,NEK2,COL27A1B,THAP7,TGFBR1B,FGD6 |
| transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | TRP53,LEF1,CEBPZ,ALS2CR8,FOSB,ZFP750,NFIB,POU1F1,TFAP2E,CREB1 |
Interacting Protein
KLF13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KLF13 here. Most of them are supplied by our site. Hope this information will be useful for your research of KLF13.
PRPF4B;GATA4;a_b_ccl5 promoter;GATA6;Srsf1
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References
- Mrad, MF; Mouawad, CA; et al. Statins modulate transcriptional activity of heme-oxygenase-1 promoter in NIH 3T3 Cells. JOURNAL OF CELLULAR BIOCHEMISTRY 113:3466-3475(2012).
- Wang, SP; Zhou, HJ; et al. Loss of expression of kruppel-like factor 6 in primary hepatocellular carcinoma and hepatoma cell lines. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH 26:117-124(2007).
- Jenkins, TD; Nakagawa, H; et al. The keratinocyte-specific Epstein-Barr virus ED-L2 promoter is regulated by phorbol 12-myristate 13-acetate through two cis-regulatory elements containing E-box and Kruppel-like factor motifs. JOURNAL OF BIOLOGICAL CHEMISTRY 272:24433-24442(1997).
