KIF3A

  • Official Full Name

    kinesin family member 3A

  • Overview

    Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro.

  • Synonyms

    KIF3A;kinesin family member 3A;FLA10;KLP-20;kinesin-like protein KIF3A;kinesin family protein 3A;microtubule plus end-directed kinesin motor 3A

Recombinant Proteins

  • Human
  • Chicken
  • Zebrafish
  • Mouse
  • E.coli
  • Mammalian Cells
  • HEK293
  • GST
  • His
  • Non
  • DDK&Myc
  • Avi&Fc&His
Cat.# Product name Source (Host) Species Tag Protein Length Price
KIF3A-373H Recombinant Human KIF3A, GST-tagged E.coli Human GST 1-355aa
KIF3A-2331C Recombinant Chicken KIF3A Mammalian Cells Chicken His
KIF3A-2377Z Recombinant Zebrafish KIF3A Mammalian Cells Zebrafish His
KIF3A-8643M Recombinant Mouse KIF3A Protein Mammalian Cells Mouse His
KIF3A-930HCL Recombinant Human KIF3A cell lysate Human Non
Kif3a-1267M Recombinant Mouse Kif3a Protein, MYC/DDK-tagged HEK293 Mouse DDK&Myc
KIF3A-4485H Recombinant Human KIF3A Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human DDK&Myc
KIF3A-4816M Recombinant Mouse KIF3A Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
KIF3A-4816M-B Recombinant Mouse KIF3A Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    KIF3A involved in several pathways and played different roles in them. We selected most pathways KIF3A participated on our site, such as Activation of SMO,Adaptive Immune System,Assembly of the primary cilium, which may be useful for your reference. Also, other proteins which involved in the same pathway with KIF3A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adaptive Immune System SPTBN2,MGC174152,LILRA1,KIF11,ICAM4,THEM4,SPSB4,SIGLEC10,CD226,NRG4
    Hedgehog signaling events mediated by Gli proteins CSNK1G3,MTSS1,SIN3B,SAP18,LGALS3,IFT88,CSNK1G2,SPOP,SAP30
    Endochondral Ossification NKX3.2,MMP13,RUNX3,RUNX2A,COL10A1,COL2A1,SOX9A,CDKN1C,COL10A1A,SOX5
    Hedgehog on state GPR161,RPGRIP1L,EFCAB7,BOC,CDON,KIF7,IQCE,SPOP,MKS1,IFT172
    Factors involved in megakaryocyte development and platelet production KLC3,AKAP1B,MYB,KIF18A,KIF5A,OSTN,IRF2A,D-AKAP2,GATA2A,KIFAP3
    Hedgehog off state WDR35,BBS13,TTC21B,MKS1,GPR161,RPGRIP1L,IFT88,TULP3,KIF7,WDR19
    Assembly of the primary cilium CNGA5,IFT27,NINL,HSPB11,FLR,DYNC1I2,IFT46,CCT3,RPGRIP1L,TCTN3
    Activation of SMO CDON,EVC2,GAS8,ADRBK1,EFCAB7,IQCE,SETD6,BOC,EVC,CSNK1A1

    Protein Function

    KIF3A has several biochemical functions, for example, ATP binding,ATP-dependent microtubule motor activity, plus-end-directed,microtubule binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KIF3A itself. We selected most functions KIF3A had, and list some proteins which have the same functions with KIF3A. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding ABCD3B,DDX51,FICD,CKMT1,SRPK1,ATAD2,UBA7,UBE2NB,SEPHS1,CSNK1G2
    spectrin binding MYO7A,DYNC1I1,GNB1,SLC26A5,USH1C,PTPRN,EPB41,ADD2,MYO10,ANK1
    microtubule binding KIF5B,MAP1LC3B,KIF1C,S100A8,MACF1,REEP4,KIAA1128,NDRG1,RACGAP1,KIF23
    protein binding PPP4R4,RAB10,PNMA2,TMEM190,MAD2L1BP,EED,CTRC,RFPL4,RBP5,KAL1
    ATP-dependent microtubule motor activity, plus-end-directed KIF5AA,KIF14,KIF17,KIF5C,KIF19,KIF18A,KIF11,KIF1C,KIF5B,KIF1B

    Interacting Protein

    KIF3A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KIF3A here. Most of them are supplied by our site. Hope this information will be useful for your research of KIF3A.

    KIFAP3;USP7;RAB11FIP5;TULP3;ARRB2;GRB2;NEK1;PLEKHA5;DISC1;KIF3C;GAK;KIF3B;Kif3c

    Resources

    Gene Families

    What Is Kinesins Gene Family

    References

    • Contini, M; Lin, B; et al. Synaptic Input of ON-Bipolar Cells onto the Dopaminergic Neurons of the Mouse Retina. JOURNAL OF COMPARATIVE NEUROLOGY 518:2035-2050(2010).
    • Brown, CL; Maier, KC; et al. Kinesin-2 is a motor for late endosomes and lysosomes. TRAFFIC 6:1114-1124(2005).

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