KIF23
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Official Full Name
kinesin family member 23 -
Overview
The protein encoded by this gene is a member of kinesin-like protein family. This family includes microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. This protein has been shown to cross-bridge antiparallel microtubules and drive microtubule movement in vitro. Alternate splicing of this gene results in two transcript variants encoding two different isoforms. -
Synonyms
KIF23;kinesin family member 23;kinesin like 5 (mitotic kinesin like protein 1) , KNSL5;kinesin-like protein KIF23;MKLP 1;MKLP1;CHO 1;CHO1;KIF 23;Kinesin Like 5;Kinesin like protein 5;Kinesin like protein KIF 23;Kinesin like protein KIF23;KNS L5;KNSL 5;KNSL5;Mitotic kinesin like 1;Mitotic kinesinlike protein 1;kinesin-like protein 5;mitotic kinesin-like 1;mitotic kinesin-like protein 1;kinesin-like 5 (mitotic kinesin-like protein 1);MKLP-1
Recombinant Proteins
- Human
- Chicken
- Mouse
- Zebrafish
- E.coli
- Mammalian Cells
- HEK293
- GST
- His
- Non
- Avi&Fc&His
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| KIF23-3692H | Recombinant Human KIF23 protein, GST-tagged | E.coli | Human | GST | 486-683 aa | |
| KIF23-2268C | Recombinant Chicken KIF23 | Mammalian Cells | Chicken | His |
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| KIF23-8635M | Recombinant Mouse KIF23 Protein | Mammalian Cells | Mouse | His |
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| KIF23-8935Z | Recombinant Zebrafish KIF23 | Mammalian Cells | Zebrafish | His |
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| KIF23-928HCL | Recombinant Human KIF23 cell lysate | Human | Non |
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| KIF23-4812M | Recombinant Mouse KIF23 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| KIF23-4812M-B | Recombinant Mouse KIF23 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
KIF23 involved in several pathways and played different roles in them. We selected most pathways KIF23 participated on our site, such as MicroRNAs in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with KIF23 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| MicroRNAs in cancer | Casp3,SHC1,ABCC1,MTOR,MAPK1,SOCS1,TRP63,EP300,CYP24A1,TNXB |
Protein Function
KIF23 has several biochemical functions, for example, ATP binding,ATPase activity,microtubule binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KIF23 itself. We selected most functions KIF23 had, and list some proteins which have the same functions with KIF23. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| microtubule binding | KIF18B,MAST2,MAP6D1,TXNDC3,CETN2,PRC1,KATNAL2,PAFAH1B1,GLI1,PLK1 |
| ATP binding | ATP2C1,ABCC3,KIF3CB,XRCC2,DDR2,ABL1,GART,AK4,GLYCTK,EIF4A1 |
| microtubule motor activity | KIF3CB,KIF25,KIF13B,KIF12,DYNC1H1,DYNC1I2,KIF2A,KIF27,DYNLRB2,KIF6 |
| ATPase activity | KIF9,HLTF,KIF3CB,ERCC3,ABCB3L1,EIF4A2,ABCB1A,ABCB6,ABCD1,VWA8 |
| protein binding | CAND2,PAK3,Apba1,METAP2,DIS3L,TNFAIP3,FGA,IRF6,NARG2,TSHR |
Interacting Protein
KIF23 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KIF23 here. Most of them are supplied by our site. Hope this information will be useful for your research of KIF23.
RACGAP1;YWHAZ;YWHAG
Resources
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References
- Hong, M; Kim, RN; et al. HIP1-ALK, a Novel Fusion Protein Identified in Lung Adenocarcinoma. JOURNAL OF THORACIC ONCOLOGY 9:419-422(2014).
- Su, YY; Ye, MY; et al. KIF5B Promotes the Forward Transport and Axonal Function of the Voltage-Gated Sodium Channel Na(v)1.8. JOURNAL OF NEUROSCIENCE 33:17884-17896(2013).
