KIF22
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Official Full Name
kinesin family member 22 -
Overview
The protein encoded by this gene is a member of kinesin-like protein family. This family of proteins are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. The C-terminal half of this protein has been shown to bind DNA. Studies with the Xenopus homolog suggests its essential role in metaphase chromosome alignment and maintenance. -
Synonyms
KIF22;kinesin family member 22;kinesin like 4 , KNSL4;kinesin-like protein KIF22;Kid;OBP 1;OBP 2;A 328A3.2;KIF 22;Kinesin like 4;Kinesin like DNA binding protein;Kinesin like DNA binding protein pseudogene;Kinesin like protein 4;Kinesin like protein KIF22;KNSL 4;KNSL4;OBP;OBP1;OBP2;Origin of plasmid DNA replication binding protein;OriP binding protein;OTTHUMP00000123406;kinesin-like 4;kinesin-like protein 4;kinesin-like DNA-binding protein pseudogene;origin of plasmid DNA replication-binding protein;OBP-1;OBP-2;A-328A3.2
Recombinant Proteins
- Human
- Rat
- Zebrafish
- Mouse
- E.coli
- Mammalian Cells
- HEK293
- His
- Non
- Avi&Fc&His
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| KIF22-3109H | Recombinant Human KIF22 protein, His-tagged | E.coli | Human | His | 4 - 353 aa | |
| KIF22-3254R | Recombinant Rat KIF22 Protein | Mammalian Cells | Rat | His |
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| KIF22-6328Z | Recombinant Zebrafish KIF22 | Mammalian Cells | Zebrafish | His |
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| KIF22-8634M | Recombinant Mouse KIF22 Protein | Mammalian Cells | Mouse | His |
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| KIF22-927HCL | Recombinant Human KIF22 cell lysate | Human | Non |
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| KIF22-2910R | Recombinant Rat KIF22 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | Avi&Fc&His |
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| KIF22-2910R-B | Recombinant Rat KIF22 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| KIF22-4811M | Recombinant Mouse KIF22 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| KIF22-4811M-B | Recombinant Mouse KIF22 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
KIF22 involved in several pathways and played different roles in them. We selected most pathways KIF22 participated on our site, such as Adaptive Immune System,Factors involved in megakaryocyte development and platelet production,Hemostasis, which may be useful for your reference. Also, other proteins which involved in the same pathway with KIF22 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Factors involved in megakaryocyte development and platelet production | IRF1B,H3F3B.1,AKAP1,HBE1,HBBE1.1,KIF20A,SH2B3,PHF21A,HBG2,KIF5B |
| Adaptive Immune System | OSBPL1A,CLEC2G,ASB14,UFL1,ITPR2,LTN1,RASGRP1,BLMH,RAET1E,UBE2V2 |
| Kinesins | KIF2B,KIF3C,KLC3,KIF2C,KIF4,KIF20A,KIF15,KIF11,KIF2A,CENPE |
| Immune System | PLD4,PVRL2L,ACTR1A,IRF4,TRIM26,LAT2,CD207,CXADR,SOCS3A,LTN1 |
| MHC class II antigen presentation | MGC174857,MGC174155,RACGAP1,FAM49BA,KIFAP3,DCTN6,KLC3,CTSC,CTSLL,DYNC1I1 |
| Hemostasis | SLC7A11,TRPC3,STXBP3A,APOA1B,NFE2,MFN1,KIF2C,EHD1,BRPF3,HBBE3 |
Protein Function
KIF22 has several biochemical functions, for example, ATP binding,ATPase activity,DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KIF22 itself. We selected most functions KIF22 had, and list some proteins which have the same functions with KIF22. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | CFTR,CKMA,ACVRL1,ILK,ABCG2C,OAS1B,ITK,TRPM4,MAP2K4A,GRK6 |
| DNA binding | SIX6B,POU2F1B,KLF12,CERS5,GCM1,YY1,TSN,LMX1BB,SOX3,NKX1.2LA |
| protein binding | WLS,HAT1,EDAR,ARRB1,RNMT,NRP1,BCL10,KCNB1,PEX2,HNRPDL |
| ATPase activity | ABCG2B,KIF12,ABCF1,RALBP1,KIF14,ENTPD2,ABCG5,HLTF,CENPE,EIF4A2 |
| microtubule binding | CENPE,KIF20A,KIF1C,NDEL1B,PSRC1,PRC1B,S100A8,KIF14,CAMSAP2A,SNCA |
| microtubule motor activity | APPBP2,KLC1A,KIF1B,KIF15,DYNC1H1,KIF23,KIF4A,KIFC2,KLC1B,KLC1 |
Interacting Protein
KIF22 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KIF22 here. Most of them are supplied by our site. Hope this information will be useful for your research of KIF22.
CRK;SVIL;GDF9;ATXN1;IMMT;PJA1;PSEN2;KPNA3;KPNA4;BCL2L11;MARCH6;MPDZ;CD2BP2;C4B;CCNB1;COX5A;RPL10;FUS;STAT6;LIMS1
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References
- Albracht, CD; Rank, KC; et al. Kinesin-2 KIF3AB Exhibits Novel ATPase Characteristics*. JOURNAL OF BIOLOGICAL CHEMISTRY 289:27836-27848(2014).
- Przybyl, J; Sciot, R; et al. Metastatic potential is determined early in synovial sarcoma development and reflected by tumor molecular features. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY 53:505-513(2014).
