KIAA1303
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Official Full Name
RPTOR regulatory associated protein of MTOR, complex 1 -
Overview
This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene. -
Synonyms
KOG1;Mip1;KIAA1303;regulatory-associated protein of mTOR;raptor;p150 target of rapamycin (TOR)-scaffold protein containing WD-repeats
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Involved Pathway
KIAA1303 involved in several pathways and played different roles in them. We selected most pathways KIAA1303 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with KIAA1303 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
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Protein Function
KIAA1303 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by KIAA1303 itself. We selected most functions KIAA1303 had, and list some proteins which have the same functions with KIAA1303. You can find most of the proteins on our site.
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Interacting Protein
KIAA1303 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KIAA1303 here. Most of them are supplied by our site. Hope this information will be useful for your research of KIAA1303.
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