KCNS3
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Official Full Name
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3 -
Overview
Voltage-gated potassium channels form the largest and most diversified class of ion channels and are present in both excitable and nonexcitable cells. Their main functions are associated with the regulation of the resting membrane potential and the control of the shape and frequency of action potentials. The alpha subunits are of 2 types: those that are functional by themselves and those that are electrically silent but capable of modulating the activity of specific functional alpha subunits. The protein encoded by this gene is not functional by itself but can form heteromultimers with member 1 and with member 2 (and possibly other members) of the Shab-related subfamily of potassium voltage-gated channel proteins. This gene belongs to the S subfamily of the potassium channel family. -
Synonyms
KCNS3;potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3;potassium voltage-gated channel subfamily S member 3;Kv9.3;voltage-gated potassium channel protein Kv9.3;voltage-gated potassium channel subunit Kv9.3;delayed-rectifier
Recombinant Proteins
- Human
- Rat
- Mouse
- Mus musculus
- Oryctolagus cuniculus (Rabbit)
- E.coli
- Mammalian Cell
- HEK293
- E.coli expression system
- GST
- His
- His&Fc&Avi
Involved Pathway
KCNS3 involved in several pathways and played different roles in them. We selected most pathways KCNS3 participated on our site, such as Integration of energy metabolism,Metabolism,Neuronal System, which may be useful for your reference. Also, other proteins which involved in the same pathway with KCNS3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Integration of energy metabolism | KCNJ11,ARL2BP,AKAP5,MARCKSB,KCNB1,RAPGEF4,RAPGEF3,GNG13A,ARL2,GNG13B |
| Metabolism | B4GALT7,AZIN2,APOA5,ARL2,SULT1B1,OSBP,UGT1B4,BPNT1,CDO1,FMODA |
| Potassium Channels | KCND2,KCNQ2A,KCNK13B,KCNH2A,KCNJ1A.3,KCND1,KCNH2,KCNA1,KCNV1,KCNMB2 |
| Neuronal System | KCNN4,KCNJ1B,KCNQ3,KCNH1A,KCNH1,CHRNB4,PICK1,PANX2,LIN7B,KCNS3A |
| Regulation of insulin secretion | MARCKSA,SYT5,KCNS3A,KCNC2,KCNB1,ARL2BP,ARL2,MARCKSB |
| Voltage gated Potassium channels | KCNA6,KCNF1A,KCNH1A,KCNV2,KCNB2,KCNC2,KCNA6A,KCNH5,KCNAB1A,KCNH5A |
Protein Function
KCNS3 has several biochemical functions, for example, delayed rectifier potassium channel activity,potassium channel regulator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KCNS3 itself. We selected most functions KCNS3 had, and list some proteins which have the same functions with KCNS3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| potassium channel regulator activity | DRD2,SGK3,YWHAE,KCNE1,KCNIP1,DLG1,KCNMB4,ABCC9,SGK1,SGK2A |
| delayed rectifier potassium channel activity | KCNA1,KCNF1,KCNQ2A,KCNQ4,KCNA6A,KCNA6,KCNE1,KCNQ3,KCNQ5,KCNA2 |
Interacting Protein
KCNS3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KCNS3 here. Most of them are supplied by our site. Hope this information will be useful for your research of KCNS3.
HSP90AB1
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