KCNK7
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Official Full Name
potassium channel, subfamily K, member 7 -
Overview
This gene encodes a member of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel; however, it may require other non-pore-forming proteins for activity. Multiple transcript variants encoding different isoforms have been found for this gene. -
Synonyms
KCNK7;potassium channel, subfamily K, member 7;potassium channel subfamily K member 7;K2p7.1;TWIK3;Two pore domain K+ channel;potassium channel, subfamily K, member 7, isoform B
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| KCNK7-5029HCL | Recombinant Human KCNK7 293 Cell Lysate | HEK293 | Human | Non |
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| KCNK7-5030HCL | Recombinant Human KCNK7 293 Cell Lysate | HEK293 | Human | Non |
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| KCNK7-5031HCL | Recombinant Human KCNK7 293 Cell Lysate | HEK293 | Human | Non |
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| RFL28940HF | Recombinant Full Length Human Potassium Channel Subfamily K Member 7(Kcnk7) Protein, His-Tagged | E.coli | Human | His | Full L. Full Length (1-307) |
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Involved Pathway
KCNK7 involved in several pathways and played different roles in them. We selected most pathways KCNK7 participated on our site, such as Neuronal System,Potassium Channels,Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK), which may be useful for your reference. Also, other proteins which involved in the same pathway with KCNK7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Neuronal System | KCNB2,KCNA2,KCNA7,SLC1A3B,CPLX1,PANX1B,SYN3,KCNF1,GRIP1,CHRNA3 |
| Tandem pore domain potassium channels | KCNK1A,KCNK2B,KCNK1,KCNK3A,KCNK13B,DDX1,KCNK4,KCNK2,KCNK18,KCNK6 |
| Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK) | KCNK1B,KCNK6,KCNK1,KCNK1A |
| Potassium Channels | KCNH5,KCNJ1A.2,KCNK2B,KCNMA1,KCNC1B,KCNH6,KCNA5,KCND2,KCNK2,KCNB2 |
Protein Function
KCNK7 has several biochemical functions, for example, potassium channel activity,potassium ion leak channel activity,voltage-gated ion channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KCNK7 itself. We selected most functions KCNK7 had, and list some proteins which have the same functions with KCNK7. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| voltage-gated ion channel activity | KCNC2,PKD2,KCNJ2A,KCNC1B,CLIC1,CLIC6,KCNJ1A.1,SCN12AB,SCN11A,CATSPER2 |
| potassium channel activity | KCNIP4,KCNQ3,KCNK3,KCNC1B,KCNC1A,KCNV2,KCNQ4,KCNK5B,KCNF1A,KCNC3A |
| potassium ion leak channel activity | KCNK1,KCNK5A,KCNK2B,KCNK1A,KCNK9,KCNK3,TMEM175,KCNK13A,KCNK18,DDX1 |
Interacting Protein
KCNK7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KCNK7 here. Most of them are supplied by our site. Hope this information will be useful for your research of KCNK7.
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References
- Vetter, I; Hein, A; et al. Amplified Cold Transduction in Native Nociceptors by M-Channel Inhibition. JOURNAL OF NEUROSCIENCE 33:16627-16641(2013).
- Zhang, J; Zhao, ZL; et al. Atrial natriuretic peptide modulates the proliferation of human gastric cancer cells via KCNQ1 expression. ONCOLOGY LETTERS 6:407-414(2013).
