KCNJ16
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Official Full Name
potassium inwardly-rectifying channel, subfamily J, member 16 -
Overview
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, can form heterodimers with two other inward-rectifier type potassium channels. It may be involved in the regulation of fluid and pH balance. Three transcript variants encoding the same protein have been found for this gene. -
Synonyms
KCNJ16;potassium inwardly-rectifying channel, subfamily J, member 16;inward rectifier potassium channel 16;BIR9;Kir5.1;inward rectifier K+ channel KIR5.1;inward rectifier K(+) channel Kir5.1;potassium channel, inwardly rectifying subfamily J member
Recombinant Proteins
- Mouse
- Rat
- Human
- Mammalian Cell
- In vitro E. coli expression system
- HEK293
- E.coli expression system
- His
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| KCNJ16-8516M | Recombinant Mouse KCNJ16 Protein | Mammalian Cell | Mouse | His |
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| Kcnj16-322R | Recombinant Rat Kcnj16 Full Length Transmembrane protein, His-tagged | In vitro E. coli expression system | Rat | His | Full L. 1-419aa |
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| KCNJ16-4739M | Recombinant Mouse KCNJ16 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| KCNJ16-4739M-B | Recombinant Mouse KCNJ16 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| KCNJ16-948H | Recombinant Human KCNJ16 Full Length Transmembrane protein, His-tagged | In vitro E. coli expression system | Human | His | Full L. 1-418aa |
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| RFL35540RF | Recombinant Full Length Rat Inward Rectifier Potassium Channel 16(Kcnj16) Protein, His-Tagged | E.coli expression system | Rat | His | Full L. Full Length (1-419aa) |
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| RFL5310HF | Recombinant Full Length Human Inward Rectifier Potassium Channel 16(Kcnj16) Protein, His-Tagged | E.coli expression system | Human | His | Full L. Full Length (1-418aa) |
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Involved Pathway
KCNJ16 involved in several pathways and played different roles in them. We selected most pathways KCNJ16 participated on our site, such as Gastric acid secretion, which may be useful for your reference. Also, other proteins which involved in the same pathway with KCNJ16 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Gastric acid secretion | CAMK2D,KCNJ1,PRKCG,CCKBR,GAST,ATP1A2,PRKACA,ATP1B1,PRKACG,ITPR3 |
Protein Function
KCNJ16 has several biochemical functions, for example, inward rectifier potassium channel activity,voltage-gated ion channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KCNJ16 itself. We selected most functions KCNJ16 had, and list some proteins which have the same functions with KCNJ16. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| inward rectifier potassium channel activity | KCNJ11L,KCNH2,KCNJ1A.6,KCNJ8,KCNK6,KCNK1,KCNJ1B,KCNJ1A.4,KCNJ18,KCNJ4 |
| voltage-gated ion channel activity | CLIC5,SCN4AA,CACNA1SA,CX35B,KCNJ1A.5,SCN8AB,GPR89,TMEM37,KCNF1A,CACNA1SB |
Interacting Protein
KCNJ16 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KCNJ16 here. Most of them are supplied by our site. Hope this information will be useful for your research of KCNJ16.
Dlg4
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References
- Chan, KHK; Chacko, SA; et al. Genetic Variations in Magnesium-Related Ion Channels May Affect Diabetes Risk among African American and Hispanic American Women. JOURNAL OF NUTRITION 145:418-424(2015).
- Li, Q; Chen, M; et al. KCNJ11 E23K variant is associated with the therapeutic effect of sulphonylureas in Chinese type 2 diabetic patients. CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY 41:748-754(2014).
