KCNH4
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Official Full Name
potassium voltage-gated channel, subfamily H (eag-related), member 4 -
Overview
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both;functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart;rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell;volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming;(alpha) subunit. The gene is brain-specific, and located in the neocortex and the striatum. It may be involved in;cellular excitability of restricted neurons in the central nervous system. -
Synonyms
KCNH4;potassium voltage-gated channel, subfamily H (eag-related), member 4;potassium voltage-gated channel subfamily H member 4;ELK1;BEC2;Brain-specific eag-like channel 2;ELK channel 1;Ether-a-go-go K(+) channel family member;Ether-a-go-go-like potassium channel 1;Kv12.3;OTTMUSP00000002054;OTTMUSP00000002055;Potassium voltage gated channel, subfamily H (eag-related), member 4;RP23-390D17.9;Voltage-gated potassium channel subunit Kv12.3;rElk1
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
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| KCNH4-3185R | Recombinant Rat KCNH4 Protein | Mammalian Cells | Rat | His |
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| KCNH4-2841R | Recombinant Rat KCNH4 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| KCNH4-2841R-B | Recombinant Rat KCNH4 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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Involved Pathway
KCNH4 involved in several pathways and played different roles in them. We selected most pathways KCNH4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with KCNH4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
KCNH4 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by KCNH4 itself. We selected most functions KCNH4 had, and list some proteins which have the same functions with KCNH4. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
KCNH4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KCNH4 here. Most of them are supplied by our site. Hope this information will be useful for your research of KCNH4.
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References
- Ramirez, A; Hinojosa, LM; et al. KCNH1 potassium channels are expressed in cervical cytologies from pregnant patients and are regulated by progesterone. REPRODUCTION 146:615-623(2013).
