KCNG1
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Official Full Name
potassium voltage-gated channel, subfamily G, member 1 -
Overview
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This gene is abundantly expressed in skeletal muscle. Multiple alternatively spliced transcript variants have been found in normal and cancerous tissues. -
Synonyms
KCNG1;potassium voltage-gated channel, subfamily G, member 1;KCNG;potassium voltage-gated channel subfamily G member 1;K13;kH2;Kv6.1;potassium channel KH2;potassium channel Kv6.1;voltage-gated potassium channel subunit Kv6.1;MGC12878
Recombinant Proteins
- Human
- Zebrafish
- Mus musculus
- E.coli
- Mammalian Cell
- HEK293
- E.coli expression system
- GST
- His
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| KCNG1-244H | Recombinant Human KCNG1, GST-tagged | E.coli | Human | GST | 1-230aa | |
| KCNG1-6166Z | Recombinant Zebrafish KCNG1 | Mammalian Cell | Zebrafish | His |
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| KCNG1-662H | Recombinant Human KCNG1 | Mammalian Cell | Human | His |
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| KCNG1-3192H | Recombinant Human KCNG1 Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
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| KCNG1-3192H-B | Recombinant Human KCNG1 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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| RFL21714MF | Recombinant Full Length Mouse Potassium Voltage-Gated Channel Subfamily G Member 1(Kcng1) Protein, His-Tagged | E.coli expression system | Mus musculus | His | Full L. Full Length (1-514) |
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| RFL6593HF | Recombinant Full Length Human Potassium Voltage-Gated Channel Subfamily G Member 1(Kcng1) Protein, His-Tagged | E.coli expression system | Human | His | Full L. Full Length (1-513) |
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Involved Pathway
KCNG1 involved in several pathways and played different roles in them. We selected most pathways KCNG1 participated on our site, such as Neuronal System,Potassium Channels,Voltage gated Potassium channels, which may be useful for your reference. Also, other proteins which involved in the same pathway with KCNG1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Voltage gated Potassium channels | KCNH5A,KCNH2A,KCNS3,KCNA10,KCNS3A,KCNH5,KCNAB1,KCNA2B,KCNAB3,KCNQ3 |
| Potassium Channels | KCNC4,KCNMB1,KCNK10B,KCNA6A,KCNA2B,KCNK16,KCNH2A,KCNJ1A.2,KCNA5,KCNA1 |
| Neuronal System | KCNJ1A.2,CHRNE,KCNG3,KCNB2,KCNN3,ARL6IP5A,SLC18A3A,KCNC1B,KCNH6A,KCNJ1A.1 |
Protein Function
KCNG1 has several biochemical functions, for example, delayed rectifier potassium channel activity,potassium channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KCNG1 itself. We selected most functions KCNG1 had, and list some proteins which have the same functions with KCNG1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| potassium channel activity | KCNK2B,KCNIP4,KCNK5A,ABCC9,TRPM5,KCNK1A,KCNK18,KCNK1,KCNQ2,KCNB2 |
| delayed rectifier potassium channel activity | KCNF1A,KCND1,KCNS3A,KCNA5,KCNQ2A,KCNA10,KCNG3,KCNB1,KCNA1,KCNG4A |
Interacting Protein
KCNG1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KCNG1 here. Most of them are supplied by our site. Hope this information will be useful for your research of KCNG1.
Resources
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References
- Chen, XD; Yang, YJ; et al. Several Polymorphisms of KCNQ1 Gene Are Associated with Plasma Lipid Levels in General Chinese Populations. PLOS ONE 7:-(2012).
- Hashimoto, R; Ohi, K; et al. The KCNH2 gene is associated with neurocognition and the risk of schizophrenia. WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY 14:114-120(2013).
