KCNF1
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Official Full Name
potassium voltage-gated channel, subfamily F, member 1 -
Overview
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily F. This gene is intronless and expressed in all tissues tested, including the heart, skeletal muscle, brain, kidney, and pancreas. -
Synonyms
KCNF1;potassium voltage-gated channel, subfamily F, member 1;KCNF;potassium voltage-gated channel subfamily F member 1;IK8;kH1;Kv5.1;IK 8;KCNF 1;KCNF1_HUMAN;kH 1;MGC33316;Potassium channel KH1;Potassium channel Kv5.1;Potassium voltage gated channel subfamily F member 1;Voltage gated potassium channelsubunit Kv5.1;Voltage-gated potassium channel subunit Kv5.1;OTTHUMP00000147594
Recombinant Proteins
- Human
- Rhesus macaque
- Mouse
- Mus musculus
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- E.coli expression system
- GST
- His
- Myc&DDK
- His&Fc&Avi
Involved Pathway
KCNF1 involved in several pathways and played different roles in them. We selected most pathways KCNF1 participated on our site, such as Neuronal System,Potassium Channels,Voltage gated Potassium channels, which may be useful for your reference. Also, other proteins which involved in the same pathway with KCNF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Voltage gated Potassium channels | KCNQ3,KCNG1,KCND1,KCNG4A,KCNC1A,KCNA7,KCNF1A,KCNQ2,KCNQ2A,KCNC2 |
| Neuronal System | KCNK1B,KCNJ1,PANX2,KCNN1B,SNAP25A,KCNMB1,CHRNB2,SNAP25B,SLC1A7B,KCNN4 |
| Potassium Channels | KCNK16,KCNH5A,KCNS3,KCNN4,KCNC4,KCNK1B,KCNA5,KCNH5,KCNJ1A.6,KCNJ1B |
Protein Function
KCNF1 has several biochemical functions, for example, delayed rectifier potassium channel activity,potassium channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KCNF1 itself. We selected most functions KCNF1 had, and list some proteins which have the same functions with KCNF1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| potassium channel activity | KCNH5,KCNK1A,KCNC3B,KCNH6A,KCNK7,KCNK18,KCNF1A,KCNK13B,DDX1,TRPM5 |
| delayed rectifier potassium channel activity | KCNA2,KCNF1A,KCNA7,KCNC2,KCNG3,KCND1,KCNC3B,KCNS3,KCNB2,KCNQ2A |
Interacting Protein
KCNF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KCNF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of KCNF1.
OPRM1
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