KCNE4
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Official Full Name
potassium voltage-gated channel, Isk-related family, member 4 -
Overview
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a type I membrane protein, and a beta subunit that assembles with a potassium channel alpha-subunit to modulate the gating kinetics and enhance stability of the multimeric complex. This gene is prominently expressed in the embryo and in adult uterus. -
Synonyms
KCNE4;potassium voltage-gated channel, Isk-related family, member 4;potassium voltage-gated channel subfamily E member 4;MiRP3;Minimum potassium ion channel related peptide 3;MinK related peptide 3;Potassium channel subunit beta MiRP3;Potassium voltage gated channel subfamily E member 4;OTTHUMP00000203809;MINK-related peptide 3;minimum potassium ion channel-related peptide 3;cardiac voltage-gated potassium channel accessory subunit 4
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| KCNE4-5272Z | Recombinant Zebrafish KCNE4 | Mammalian Cell | Zebrafish | His |
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| KCNE4-8494M | Recombinant Mouse KCNE4 Protein | Mammalian Cell | Mouse | His |
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| KCNE4-5063HCL | Recombinant Human KCNE4 293 Cell Lysate | HEK293 | Human | Non |
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| KCNE4-4729M | Recombinant Mouse KCNE4 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| KCNE4-4729M-B | Recombinant Mouse KCNE4 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
KCNE4 involved in several pathways and played different roles in them. We selected most pathways KCNE4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with KCNE4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
KCNE4 has several biochemical functions, for example, ion channel binding,protein binding,voltage-gated potassium channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KCNE4 itself. We selected most functions KCNE4 had, and list some proteins which have the same functions with KCNE4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| voltage-gated potassium channel activity | KCNAB3,KCNH6,KCNK9,KCNK5,KCNC1,HCN4,CNGA5,KCNQ2,CNGA3,KCNC2 |
| protein binding | PPIA,MMS22L,PDPK1,ALPL,KCNS2,ZNF3,FAM192A,SLIT2,RPL7,YEATS4 |
| ion channel binding | KCNE1L,ACTN2,YWHAH,TRPC1,FXYD1,PACS1,PACS1A,YES1,CALM1,GRINA |
Interacting Protein
KCNE4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KCNE4 here. Most of them are supplied by our site. Hope this information will be useful for your research of KCNE4.
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