JRK
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Official Full Name
jerky homolog (mouse) -
Overview
This gene is the human homolog of the mouse jerky gene. The encoded protein has similarity to several nuclear regulatory proteins, including centromere protein B, suggesting that it might function as a DNA-binding protein. Insertional inactivation of this gene in transgenic mice resulted in epileptic seizures. Childhood Absence Epilepsy (CAE) has been mapped to the same chromosomal location (8q24.3) as this gene, making this gene a strong candidate for CAE. Two transcript variants encoding different isoforms have been found for this gene. -
Synonyms
JRK;jerky homolog (mouse);jerky (mouse) homolog;jerky protein homolog;JH8;Jerky
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| JRK-2124HCL | Recombinant Human JRK cell lysate | Human | Non |
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| Jrk-1251M | Recombinant Mouse Jrk Protein, MYC/DDK-tagged | HEK293 | Mouse | Myc&DDK |
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| JRK-5091H | Recombinant Human JRK Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | Myc&DDK |
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Involved Pathway
JRK involved in several pathways and played different roles in them. We selected most pathways JRK participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with JRK were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
JRK has several biochemical functions, for example, DNA binding,molecular_function,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by JRK itself. We selected most functions JRK had, and list some proteins which have the same functions with JRK. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| DNA binding | BACH1A,CMYB,PPP1R8,ZFAND5A,SETDB1B,HIST1H2B8,EGR4,ERCC6,HIST1H2BD,ZBTB39 |
| molecular_function | CRISPLD1,LHFPL2B,MFAP3L,SLC45A1,TPM3,CHAC2,TMEM45B,XKR8.3,VMN1R163,ZFP830 |
| protein binding | RALB,LAT,YAP1,TIMM50,KIAA0247,GLIS2,HILPDA,OTUB2,SYNPO2L,HUWE1 |
Interacting Protein
JRK has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with JRK here. Most of them are supplied by our site. Hope this information will be useful for your research of JRK.
CTNNB1;Lef1;PYGO2;TCF7L2
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References
- DRESKIN, SC; et al. A METHOD TO TRAP IGG ANTIBODIES WITHIN FUNCTIONAL MEMBRANE-VESICLES. JOURNAL OF IMMUNOLOGICAL METHODS 179:87-93(1995).
