JAZF1
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Official Full Name
JAZF zinc finger 1 -
Overview
This gene encodes a nuclear protein with three C2H2-type zinc fingers, and functions as a transcriptional repressor.;Chromosomal aberrations involving this gene are associated with endometrial stromal tumors. Alternatively spliced;variants which encode different protein isoforms have been described; however, not all variants have been fully;characterized. -
Synonyms
JAZF1;JAZF zinc finger 1;juxtaposed with another zinc finger protein 1;DKFZp761K2222;TIP27;ZNF802;TAK1 interacting protein 27;Zinc finger protein 802;TAK1-interacting protein 27;juxtaposed with another zinc finger gene 1
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| JAZF1-202H | Recombinant Human JAZF1, GST-tagged | E.coli | Human | GST | 1-243aa | |
| JAZF1-4427C | Recombinant Chicken JAZF1 | Mammalian Cell | Chicken | His |
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| JAZF1-557H | Recombinant Human JAZF zinc finger 1, His-tagged | E.coli | Human | His | 1-243 a.a. |
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| JAZF1-8417M | Recombinant Mouse JAZF1 Protein | Mammalian Cell | Mouse | His |
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| JAZF1-4673M | Recombinant Mouse JAZF1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| JAZF1-4673M-B | Recombinant Mouse JAZF1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
JAZF1 involved in several pathways and played different roles in them. We selected most pathways JAZF1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with JAZF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
JAZF1 has several biochemical functions, for example, metal ion binding,nucleic acid binding,transcription corepressor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by JAZF1 itself. We selected most functions JAZF1 had, and list some proteins which have the same functions with JAZF1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| metal ion binding | ZNF45L,IRF2BP2A,KSR1,DNLZ,ZHX3,GALNS,CA14,ZFP579,GZF1,FHL1B |
| transcription corepressor activity | TRIM28,ZHX3,ZEB1,MXD1,PRMT5,SMYD1,LIMD1,DRAP1,SRSF2,ATN1 |
| nucleic acid binding | RBM44,EWSR1B,FAM90A1,C19orf6,EAR1,CIZ1B,SPAG7,RNASE2,ZNF843,ZFP335 |
Interacting Protein
JAZF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with JAZF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of JAZF1.
YEATS4;Ruvbl1;TRRAP
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References
- Ali, RH; Al-Safi, R; et al. Molecular characterization of a population-based series of endometrial stromal sarcomas in Kuwait. HUMAN PATHOLOGY 45:2453-2462(2014).
- Lee, CH; Hoang, LN; et al. Frequent expression of KIT in endometrial stromal sarcoma with YWHAE genetic rearrangement. MODERN PATHOLOGY 27:751-757(2014).
- Croce, S; Hostein, I; et al. YWHAE rearrangement identified by FISH and RT-PCR in endometrial stromal sarcomas: genetic and pathological correlations. MODERN PATHOLOGY 26:1390-1400(2013).
- Baker, P; Oliva, E; et al. Endometrial stromal tumours of the uterus: a practical approach using conventional morphology and ancillary techniques. JOURNAL OF CLINICAL PATHOLOGY 60:235-243(2007).
