JARID1A
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Official Full Name
KDM5A lysine (K)-specific demethylase 5A -
Overview
The protein encoded by this gene is a ubiquitously expressed nuclear protein. It binds directly, with several other proteins, to retinoblastoma protein which regulates cell proliferation. This protein also interacts with rhombotin-2 which functions distinctly in erythropoiesis and in T-cell leukemogenesis. Rhombotin-2 is thought to either directly affect the activity of the encoded protein or may indirectly modulate the functions of the retinoblastoma protein by binding to this protein. -
Synonyms
RBP2;RBBP2;RBBP-2;JARID1A;lysine-specific demethylase 5A;OTTHUMP00000237742;histone demethylase JARID1A;retinoblastoma binding protein 2;retinoblastoma-binding protein 2;jumonji/ARID domain-containing protein 1A;Jumonji, AT rich interactive domain 1A (RBP2-like);Jumonji, AT rich interactive domain 1A (RBBP2-like)
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Kit-1765 | JARID1A (KDM5A) Chemiluminescent Assay Kit | Non |
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| Kit-1766 | JARID1A (KDM5A) Homogeneous Assay Kit | Non |
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Involved Pathway
JARID1A involved in several pathways and played different roles in them. We selected most pathways JARID1A participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with JARID1A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
JARID1A has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by JARID1A itself. We selected most functions JARID1A had, and list some proteins which have the same functions with JARID1A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
JARID1A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with JARID1A here. Most of them are supplied by our site. Hope this information will be useful for your research of JARID1A.
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