Hsd3b5
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Official Full Name
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5 -
Synonyms
Hsd1;Hsd3b;RATHSDI
Recombinant Proteins
- Rat
- Mouse
- Mus musculus
- Mammalian Cell
- HEK293
- E.coli expression system
- His
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| HSD3B5-2934R | Recombinant Rat HSD3B5 Protein | Mammalian Cell | Rat | His |
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| HSD3B5-7886M | Recombinant Mouse HSD3B5 Protein | Mammalian Cell | Mouse | His |
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| HSD3B5-2589R | Recombinant Rat HSD3B5 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| HSD3B5-2589R-B | Recombinant Rat HSD3B5 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| HSD3B5-4342M | Recombinant Mouse HSD3B5 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| HSD3B5-4342M-B | Recombinant Mouse HSD3B5 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| RFL10704RF | Recombinant Full Length Rat 3 Beta-Hydroxysteroid Dehydrogenase Type 5(Hsd3B5) Protein, His-Tagged | E.coli expression system | Rat | His | Full L. Full Length of Mature Protein (2-373) |
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| RFL34258MF | Recombinant Full Length Mouse 3 Beta-Hydroxysteroid Dehydrogenase Type 5(Hsd3B5) Protein, His-Tagged | E.coli expression system | Mus musculus | His | Full L. Full Length of Mature Protein (2-373) |
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Involved Pathway
Hsd3b5 involved in several pathways and played different roles in them. We selected most pathways Hsd3b5 participated on our site, such as Steroid hormone biosynthesis,Metabolic pathways,Ovarian steroidogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with Hsd3b5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Ovarian steroidogenesis | INS2,ALOX5,LDLR,SCARB1,LHB,PRKACA,PRKACG,BMP6,PLA2G4C,CYP2J6 |
| Aldosterone synthesis and secretion | PRKACB,PRKACG,AGTR1A,CALM4,KCNK3,PLCB1,CYP21A2,CAMK2D,CALML3,HSD3B4 |
| Metabolic pathways | COX17,CHDH,STT3B,AMY2A4,KYNU,ATP6V1H,ALDH2,PHOSPHO1,CYP2R1,REV3L |
| Steroid hormone biosynthesis | UGT1A4,CYP2C55,UGT1A6A,UGT1A1,SRD5A2,HSD3B4,SRD5A2A,CYP2B19,COMTB,CYP2C54 |
Protein Function
Hsd3b5 has several biochemical functions, for example, (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity,(R)-2-hydroxyglutarate dehydrogenase activity,(R)-2-hydroxyisocaproate dehydrogenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Hsd3b5 itself. We selected most functions Hsd3b5 had, and list some proteins which have the same functions with Hsd3b5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| 3-hydroxymenthone dehydrogenase activity | SDR16C6,AKR1C21,SDR42E1,H2-KE6,HSD3B6,AKR1C6,HSD11B1LA |
| gluconate dehydrogenase activity | HSD3B6,AKR1C21,HSD11B1LA,SDR42E1,H2-KE6,SDR16C6,AKR1C6 |
| steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | AKR1C6,HSD11B1LA,SDR42E1,HSD3B6,H2-KE6,SDR16C6,AKR1C21 |
| (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity | H2-KE6,SDR16C6,HSD11B1LA,HSD3B6,SDR42E1,AKR1C6,AKR1C21 |
| (R)-2-hydroxyglutarate dehydrogenase activity | AKR1C21,HSD3B6,H2-KE6,SDR16C6,SDR42E1,D2HGDH,AKR1C6,HSD11B1LA |
| steroid dehydrogenase activity | H2-KE6,AKR1C6,AKR1C21,HSD11B1LA,HSD3B6,HSD17B11,SDR42E1,SDR16C6 |
| mevaldate reductase activity | SDR42E1,AKR1C6,HSD11B1LA,SDR16C6,HSD3B6,H2-KE6,AKR1C21 |
| steroid binding | ESR2,PAQR5,HSD17B10,PAQR5A,SULT1E1,HSD3B4,PGR,PGRMC2,PAQR7A,GPR30 |
| L-xylulose reductase (NAD+) activity | SDR42E1,AKR1C6,HSD3B6,AKR1C21,H2-KE6,SDR16C6,HSD11B1LA |
Interacting Protein
Hsd3b5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Hsd3b5 here. Most of them are supplied by our site. Hope this information will be useful for your research of Hsd3b5.
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