Helb
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Official Full Name
HELB helicase (DNA) B [ Homo sapiens ] -
Overview
This gene encodes a DNA-dependent ATPase which catalyzes the unwinding of DNA necessary for DNA replication, repair, recombination, and transcription. This gene is thought to function specifically during the S phase entry of the cell cycle. -
Synonyms
helicase (DNA) B;17196;Ensembl:ENSG00000127311;DNA helicase B;helicase B;3.6.4.12;hDHB
Recombinant Proteins
- Human
- Mouse
- Rhodobacter capsulatus
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- E.coli expression system
- GST
- His
- Myc&DDK
- His&Fc&Avi
Involved Pathway
Helb involved in several pathways and played different roles in them. We selected most pathways Helb participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with Helb were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
Helb has several biochemical functions, for example, ATP binding,ATP-dependent 5-3 DNA helicase activity,NOT ATP-dependent RNA helicase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Helb itself. We selected most functions Helb had, and list some proteins which have the same functions with Helb. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP-dependent 5-3 DNA helicase activity | IGHMBP2,DOM3Z,PIF1,RUVBL2,NUDT19 |
| ATP binding | ABCG1,PKN3,MYH4,OASL,MAP3K12,KIF4A,PFKFB2,PRPS2,ACVRL1,MCM6L |
| single-stranded DNA-dependent ATP-dependent DNA helicase activity | PIF1 |
Interacting Protein
Helb has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Helb here. Most of them are supplied by our site. Hope this information will be useful for your research of Helb.
q8d0h6_yerpe;RPA2;RPA1;RPA3;Sept9
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