HSPA12B
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Official Full Name
heat shock 70kD protein 12B -
Overview
The protein encoded by this gene contains an atypical heat shock protein 70 (Hsp70) ATPase domain and is therefore a distant member of the mammalian Hsp70 family. This gene may be involved in susceptibility to atherosclerosis. Alternative splicing results in multiple transcript variants. -
Synonyms
HSPA12B;heat shock 70kD protein 12B;C20orf60, chromosome 20 open reading frame 60;heat shock 70 kDa protein 12B;dJ1009E24.2;C20orf60;FLJ32150;MGC131912
Recombinant Proteins
- Zebrafish
- Human
- Mouse
- Mammalian Cell
- Wheat Germ
- HEK293
- E.coli
- In Vitro Cell Free System
- HEK293T
- His
- GST
- Non
- His&T7
- His&Fc&Avi
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| HSPA12B-3817Z | Recombinant Zebrafish HSPA12B | Mammalian Cell | Zebrafish | His |
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| HSPA12B-5101H | Recombinant Human HSPA12B Protein, GST-tagged | Wheat Germ | Human | GST |
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| HSPA12B-7901M | Recombinant Mouse HSPA12B Protein | Mammalian Cell | Mouse | His |
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| HSPA12B-5359HCL | Recombinant Human HSPA12B 293 Cell Lysate | HEK293 | Human | Non |
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| HSPA12B-1479H | Recombinant Human HSPA12B protein, His & T7-tagged | E.coli | Human | His&T7 | Met1~Gln217 |
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| HSPA12B-3809HF | Recombinant Full Length Human HSPA12B Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 686 amino acids |
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| HSPA12B-4352M | Recombinant Mouse HSPA12B Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| HSPA12B-4352M-B | Recombinant Mouse HSPA12B Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| HSPA12B-5492H | Recombinant Human HSPA12B Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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Involved Pathway
HSPA12B involved in several pathways and played different roles in them. We selected most pathways HSPA12B participated on our site, such as Cellular response to heat stress,Cellular responses to stress,Regulation of HSF1-mediated heat shock response, which may be useful for your reference. Also, other proteins which involved in the same pathway with HSPA12B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Regulation of HSF1-mediated heat shock response | C11orf73,HSPA13,HSPA7,ST13,BAG3,BAG5,DNAJC7,DNAJB6,KIAA1967,RPS19BP1 |
| Cellular response to heat stress | ST13,HSPA13,MAPKAPK2B,NUPL2,DNAJB6,HSBP1A,HSPA14,HSBP1B,C11orf73,EEF1A1 |
| Cellular responses to stress | ATG9B,MINK1,CDKN2B,WIPI1,UVRAG,AMBRA1B,HIST3H2BB,KAT5,H1F0,AMBRA1A |
Protein Function
HSPA12B has several biochemical functions, for example, ATP binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HSPA12B itself. We selected most functions HSPA12B had, and list some proteins which have the same functions with HSPA12B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | KIF19,MAPK8,KIF21A,DNAJA1,SPO11,NUAK1,TOR2A,AK8,ABCG2A,DDX39AA |
| protein binding | CHERP,FABP5,ERLEC1,TREX1,BRD3,STRADA,GGPS1,FBXO18,NCBP2,ZNF335 |
Interacting Protein
HSPA12B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HSPA12B here. Most of them are supplied by our site. Hope this information will be useful for your research of HSPA12B.
KRT31;KRT40;NOTCH2NL
Resources
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References
- Steagall, RJ; Rusinol, AE; et al. HSPA12B is predominantly expressed in endothelial cells and required for angiogenesis. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 26:2012-2018(2006).
