HR
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Official Full Name
hair growth associated -
Overview
This gene encodes a protein that is involved in hair growth. This protein functions as a transcriptional corepressor of multiple nuclear receptors, including thyroid hormone receptor, the retinoic acid receptor-related orphan receptors and the vitamin D receptors, and it interacts with histone deacetylases. The translation of this protein is modulated by multiple regulatory ORFs that exist upstream of the primary ORF. Mutations in one of these upstream ORFs, U2HR, cause Marie Unna hereditary hypotrichosis (MUHH), an autosomal dominant form of genetic hair loss. Mutations in this gene also cause autosomal recessive congenital alopecia and atrichia with papular lesions, other diseases resulting in hair loss. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009] -
Synonyms
HR;hair growth associated;AU;MUHH;ALUNC;MUHH1;HSA277165;protein hairless;hairless homolog
Recombinant Proteins
- Human
- Rhesus macaque
- Mouse
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293T
- HEK293
- GST
- His
- Myc&DDK
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| HR-13933H | Recombinant Human HR, GST-tagged | E.coli | Human | GST | 351-700a.a. | |
| HR-2140R | Recombinant Rhesus monkey HR Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| HR-5022H | Recombinant Human HR Protein, GST-tagged | Wheat Germ | Human | GST |
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| HR-7841M | Recombinant Mouse HR Protein | Mammalian Cell | Mouse | His |
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| Hr-1168M | Recombinant Mouse Hr Protein, MYC/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| HR-1887H | Recombinant Human HR Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| HR-1961R | Recombinant Rhesus Macaque HR Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| HR-1961R-B | Recombinant Rhesus Macaque HR Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| HR-3980H | Recombinant Human HR Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| HR-4313M | Recombinant Mouse HR Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| HR-4313M-B | Recombinant Mouse HR Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
HR involved in several pathways and played different roles in them. We selected most pathways HR participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with HR were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
HR has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by HR itself. We selected most functions HR had, and list some proteins which have the same functions with HR. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
HR has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HR here. Most of them are supplied by our site. Hope this information will be useful for your research of HR.
VDR;ESR2
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References
- Mukherjee, R; Sinha, A; et al. Utilization of Zero Valent Iron (ZVI) Particles Produced from Steel Industry Waste for In-Situ Remediation of Ground Water Contaminated with Organo-Chlorine Pesticide Heptachlor. INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH 9:19-26(2015).
- Rywinska, A; Marcinkiewicz, M; et al. Optimization of Medium Composition for Erythritol Production from Glycerol by Yarrowia lipolytica Using Response Surface Methodology. PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY 45:515-529(2015).
