HOXC4
-
Official Full Name
homeobox C4 -
Overview
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene, HOXC4, is one of several homeobox HOXC genes located in a cluster on chromosome 12. Three genes, HOXC5, HOXC4 and HOXC6, share a 5 non-coding exon. Transcripts may include the shared exon spliced to the gene-specific exons, or they may include only the gene-specific exons. Two alternatively spliced variants that encode the same protein have been described for HOXC4. Transcript variant one includes the shared exon, and transcript variant two includes only gene-specific exons. -
Synonyms
HOXC4;homeobox C4;homeo box C4 , HOX3, HOX3E;homeobox protein Hox-C4;CP 19;CP19;Homeo box 3E;Homeo box C4;Homeo box protein HoxC4;Homeobox 3E;Homeobox protein CP19;Homeobox protein Hox C4;Homeobox protein Hox-3E;Homeobox protein HoxC4;Homeobox3E;HomeoboxC4;HOX 3;Hox 3E;HOX C4;HOX3;Hox3E;HOXC 4;HXC4_HUMAN;OTTHUMP00000217392;OTTHUMP00000217393
Recombinant Proteins
- Human
- Rhesus macaque
- Mouse
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- GST
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| HOXC4-13905H | Recombinant Human HOXC4, GST-tagged | E.coli | Human | GST | 1-264a.a. | |
| HOXC4-2133R | Recombinant Rhesus monkey HOXC4 Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
|
|
| HOXC4-28513TH | Recombinant Human HOXC4 | Wheat Germ | Human | Non | 105 amino acids |
|
| HOXC4-4979H | Recombinant Human HOXC4 Protein, GST-tagged | Wheat Germ | Human | GST |
|
|
| HOXC4-7808M | Recombinant Mouse HOXC4 Protein | Mammalian Cell | Mouse | His |
|
|
| HOXC4-5417HCL | Recombinant Human HOXC4 293 Cell Lysate | HEK293 | Human | Non |
|
|
| HOXC4-1954R | Recombinant Rhesus Macaque HOXC4 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
|
|
| HOXC4-1954R-B | Recombinant Rhesus Macaque HOXC4 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
|
||
| HOXC4-3726HF | Recombinant Full Length Human HOXC4 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 264 amino acids |
|
| HOXC4-4292M | Recombinant Mouse HOXC4 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
|
|
| HOXC4-4292M-B | Recombinant Mouse HOXC4 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
|
Involved Pathway
HOXC4 involved in several pathways and played different roles in them. We selected most pathways HOXC4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with HOXC4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
HOXC4 has several biochemical functions, for example, HMG box domain binding,protein binding,sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HOXC4 itself. We selected most functions HOXC4 had, and list some proteins which have the same functions with HOXC4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | RBM15,ICAM4,UCKL1,ANKRD24,UNC45A,PSMB5,SEMA4A,SYNGR1,RPL5,UNC13A |
| transcription factor activity, sequence-specific DNA binding | SHOX,TSC22D3,ZNF19,AATF,TP63,ZFP13,KDM3A,PHTF1,DBPB,FOXO3 |
| HMG box domain binding | POU3F3,PAX3,OLIG2,CEBPA,HOXA3,PRRX1,UTF1,MEOX1,JUN,EGR2 |
| sequence-specific DNA binding | EMX2,DLX4A,HOXB6,MNX2A,FOXC1A,HOXB7A,DLX4B,MAFF,FOXD5,UNCX |
Interacting Protein
HOXC4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HOXC4 here. Most of them are supplied by our site. Hope this information will be useful for your research of HOXC4.
SUV39H1;WHSC1L1;PRMT5;HTT;ELMOD2;PRMT6;RNF32
Resources
Related Services
Related Products
References
- White, CA; Pone, EJ; et al. Histone Deacetylase Inhibitors Upregulate B Cell microRNAs That Silence AID and Blimp-1 Expression for Epigenetic Modulation of Antibody and Autoantibody Responses. JOURNAL OF IMMUNOLOGY 193:5933-5950(2014).
- Zan, H; Casali, P; et al. Regulation of Aicda expression and AID activity. AUTOIMMUNITY 46:83-101(2013).
