HOXB2
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Official Full Name
homeobox B2 -
Overview
This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with pancreatic cancer. -
Synonyms
HOXB2;homeobox B2;homeo box B2 , HOX2, HOX2H;homeobox protein Hox-B2;homeo box 2H;homeo box B2;Homeobox protein Hox-2.8;Homeobox protein Hox-2H;Hox 2 8;Hox 2H;HOX2;HOX2H;HXB2_HUMAN;K8;K8 home protein;Hox-2.8
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| HOXB2-2771H | Recombinant Human HOXB2 protein, His-tagged | E.coli | Human | His | 224-312 aa | |
| HOXB2-4958H | Recombinant Human HOXB2 Protein, GST-tagged | Wheat Germ | Human | GST |
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| HOXB2-7797M | Recombinant Mouse HOXB2 Protein | Mammalian Cell | Mouse | His |
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| HOXB2-3716HF | Recombinant Full Length Human HOXB2 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 356 amino acids |
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| HOXB2-4285M | Recombinant Mouse HOXB2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| HOXB2-4285M-B | Recombinant Mouse HOXB2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
HOXB2 involved in several pathways and played different roles in them. We selected most pathways HOXB2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with HOXB2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
HOXB2 has several biochemical functions, for example, DNA binding,sequence-specific DNA binding,transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HOXB2 itself. We selected most functions HOXB2 had, and list some proteins which have the same functions with HOXB2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| DNA binding | PNN,LBX1B,ARHGAP35,FOXL2,OVOL2,MSXE,HIST2H2AA2,ZFP521,HEMK1,SIX1A |
| sequence-specific DNA binding | FOXO6,LHX2,FOXB1A,NKX2-6,GRHL2,ARX,HLX,POU3F3,HLFB,VDRA |
| transcription factor activity, sequence-specific DNA binding | ZNF75D,ARNTL1A,ZFP146,SNAPC4,SIX3,HOXB6,SLC25A46,T,SLAMF7,MAP3K7 |
Interacting Protein
HOXB2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HOXB2 here. Most of them are supplied by our site. Hope this information will be useful for your research of HOXB2.
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