HNRNPUL1

  • Official Full Name

    heterogeneous nuclear ribonucleoprotein U-like 1

  • Overview

    This gene encodes a nuclear RNA-binding protein of the heterogeneous nuclear ribonucleoprotein (hnRNP) family. This protein binds specifically to adenovirus E1B-55kDa oncoprotein. It may play an important role in nucleocytoplasmic RNA transport, and its function is modulated by E1B-55kDa in adenovirus-infected cells. Two transcript variants encoding different isoforms have been found for this gene. Additional variants have also been found, but their full-length natures have not been determined. This gene encodes a nuclear RNA-binding protein of the heterogeneous nuclear ribonucleoprotein (hnRNP) family. This;protein binds specifically to adenovirus E1B-55kDa oncoprotein. It may play an important role in nucleocytoplasmic RNA;transport, and its function is modulated by E1B-55kDa in adenovirus-infected cells. Two transcript variants encoding;different isoforms have been found for this gene. Additional variants have also been found, but their full-length;natures have not been determined.

  • Synonyms

    HNRNPUL1;heterogeneous nuclear ribonucleoprotein U-like 1;HNRPUL1;heterogeneous nuclear ribonucleoprotein U-like protein 1;E1B 55kDa associated protein 5;E1B AP5;E1BAP5;FLJ12944;fk45c03;wu:fb53d10;Adenovirus early region 1B associated protein 5;E130317O14Rik;E1B 55 kDa associated protein 5;fb53d10;MGC36621;MGC78330;wu:fk45c03;zgc:85971;E1B-55kDa-associated protein 5;E1B-55 kDa-associated protein 5;adenovirus early region 1B-associated protein 5;E1B-AP5
Cat.# Product name Source (Host) Species Tag Protein Length Price
HNRNPUL1-13877H Recombinant Human HNRNPUL1, GST-tagged E.coli Human GST 1-227a.a.
HNRNPUL1-12464Z Recombinant Zebrafish HNRNPUL1 Mammalian Cell Zebrafish His
HNRNPUL1-7770M Recombinant Mouse HNRNPUL1 Protein Mammalian Cell Mouse His
HNRNPUL1-805HCL Recombinant Human HNRNPUL1 cell lysate Human Non
HNRNPUL1-4265M Recombinant Mouse HNRNPUL1 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
HNRNPUL1-4265M-B Recombinant Mouse HNRNPUL1 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    HNRNPUL1 involved in several pathways and played different roles in them. We selected most pathways HNRNPUL1 participated on our site, such as Gene Expression,Influenza A,Processing of Capped Intron-Containing Pre-mRNA, which may be useful for your reference. Also, other proteins which involved in the same pathway with HNRNPUL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Processing of Capped Intron-Containing Pre-mRNA PCBP2,SF3B4,SRSF11,CD2BP2,HNRNPD,SNRNP25,HNRNPH1L,ZCRB1,TXNL4A,PAPOLA
    Influenza A OAS2,PRSS3,TBK1,H2-AB1,SLC25A6,Ifna15,PIK3CB,OAS1B,OAS1,TLR3
    Gene Expression ADAT1,ZNF100,DDX20,BARHL1,ZNF311,CDK8,NR5A1B,ZNF184,ZNF529,SUZ12A
    mRNA Splicing TTC6,RNPC3,HNRNPD,SF3A1,SFRS3A,DNAJC8,RBM5,PTBP1A,SNRNP25,HNRNPL2
    mRNA Splicing - Major Pathway HNRNPA0A,HNRNPA2B1,HNRNPH1L,SUGP1,HNRNPH1,PCBP2,SF3B2,HNRNPR,PTBP1B,HNRNPA0B

    Protein Function

    HNRNPUL1 has several biochemical functions, for example, RNA binding,enzyme binding,poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HNRNPUL1 itself. We selected most functions HNRNPUL1 had, and list some proteins which have the same functions with HNRNPUL1. You can find most of the proteins on our site.

    Function Related Protein
    poly(A) RNA binding RBFOX2,TFB2M,SOSTDC1B,NOC2L,RPS18,MKI67IP,APOBEC3F,CHD2,CIRH1A,PRPF40A
    RNA binding RPF1,NSUN3,TRIM32,DDX3X,CNOT4B,PDCD4,RTCD1,CTU1,EIF4G2B,PAIP1
    protein binding ISL1,ITM2C,IL6ST,PPIH,HIST1H2BB,TMEM115,ANXA6,CDH15,CUEDC2,ISOC2
    enzyme binding PARP1,ARPC4,HSPA1A,NLRP1,NPC2,TSPYL1,HIST1H2AL,SIRT1,PPP3CB,CUTA

    Interacting Protein

    HNRNPUL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HNRNPUL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of HNRNPUL1.

    TP53;WWP2;HNRNPF

    Resources

    References

    • Yamazaki, F; Kim, HH; et al. pY RNA1-s2: A Highly Retina-Enriched Small RNA That Selectively Binds to Matrin 3 (Matr3). PLOS ONE 9:-(2014).
    • Hong, ZH; Jiang, J; et al. The Role of hnRPUL1 Involved in DNA Damage Response Is Related to PARP1. PLOS ONE 8:-(2013).

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