HMTase
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Official Full Name
similar to Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor binding SET domain containing protein 1) (NR-binding SET domain containing protein) -
Overview
Set 7/9 is a histone methyltransferase (HMTase) that transfers methyl groups to Lys4 of histone H3, in complex with S-adenosyl-L-methionine (AdoMet). The methylation of lysine residues of histones plays a critical role in the regulation of chromatin structure and gene expression. Acetylation, phosphorylation and methylation of the amino-terminal tails of histone are thought to be involved in the regulation of chromatin structure and function. The enzymes identified in the methylation of specific lysine residue on histones belong to the SET family with just one exception. Set7/9, unlike most other SET proteins, is exclusively a mono-methylase. -
Synonyms
SETD7;SET7;FLJ21193;KIAA1717;KMT7;SET7/9;SET9;EC 2.1.1.43;Set9;H3-K4-HMTase;H3-K4-HMTase SETD7;H3 lysine-4 specific SET7;Histone-lysine N-methyltransferase;Histone H3-K4 methyltransferase;histone H3-lysine 4-specific methyltransferase;SET domain-containing protein 7;Histone H3-K4 methyltransferase SETD7;Lysine N-methyltransferase 7;SET domain containing (lysine methyltransferase) 7;histone H3-K4 methyltransferase;histone-lysine N-methyltransferase;protein methylase III;protein methylase 3;protein (lysine) methyltransferase;protein methyltransferase II;protein-lysine N-methyltransferase;histone H1-specific S-adenosylmethionine:protein-lysine N-methyltransferase;S-adenosyl-L-methionine:histone-L-lysine N6-methyltransferase
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| HMTase-89H | Recombinant Human Set7/9 Histone Methyltransferase | E.coli | Human | Non |
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Involved Pathway
HMTase involved in several pathways and played different roles in them. We selected most pathways HMTase participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with HMTase were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
HMTase has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by HMTase itself. We selected most functions HMTase had, and list some proteins which have the same functions with HMTase. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
HMTase has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HMTase here. Most of them are supplied by our site. Hope this information will be useful for your research of HMTase.
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