HMGN5
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Official Full Name
high mobility group nucleosome binding domain 5 -
Overview
This gene encodes a nuclear protein with similarities to the high mobility group proteins, HMG14 and HMG17, which suggests that this protein may function as a nucleosomal binding and transcriptional activating protein. -
Synonyms
HMGN5;high mobility group nucleosome binding domain 5;high mobility group nucleosome binding domain 5 , NSBP1, nucleosomal binding protein 1;high mobility group nucleosome-binding domain-containing protein 5;NSBP 1;Nucleosomal binding protein 1;Nucleosome binding protein 1;nucleosome-binding protein 1;high-mobility group nucleosome binding domain 5;NSBP1;NBP-45
Recombinant Proteins
- Rat
- Mouse
- Human
- Mammalian Cell
- E.coli
- HEK293
- His
- His&GST
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| HMGN5-2871R | Recombinant Rat HMGN5 Protein | Mammalian Cell | Rat | His |
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| HMGN5-7739M | Recombinant Mouse HMGN5 Protein | Mammalian Cell | Mouse | His |
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| HMGN5-1630H | Recombinant Human HMGN5 Protein, His&GST-tagged | E.coli | Human | His&GST | Arg19-Val282 |
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| Hmgn5-1631M | Recombinant Mouse Hmgn5 Protein, His&GST-tagged | E.coli | Mouse | His&GST | Arg20-Val172 |
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| HMGN5-2526R | Recombinant Rat HMGN5 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| HMGN5-2526R-B | Recombinant Rat HMGN5 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| HMGN5-4246M | Recombinant Mouse HMGN5 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| HMGN5-4246M-B | Recombinant Mouse HMGN5 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
HMGN5 involved in several pathways and played different roles in them. We selected most pathways HMGN5 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with HMGN5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
HMGN5 has several biochemical functions, for example, DNA binding,chromatin binding,nucleosomal DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HMGN5 itself. We selected most functions HMGN5 had, and list some proteins which have the same functions with HMGN5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| nucleosomal DNA binding | H2AFY,HMGN3,RCC1,HMGA2,HMGN2,H3F3B,HMGN4,H2AFZ,H3F3C,NSBP1 |
| chromatin binding | SOX9A,YAP1,KDM1A,NCOA1,REST,PAX3,SVEP1,TAF2,CENPB,EOMES |
| DNA binding | GSX1,RARB,ZNF643,HOXC12A,SETDB2,MCM3,EGR3,UBTFL1,HOXB13A,KDM5BA |
Interacting Protein
HMGN5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HMGN5 here. Most of them are supplied by our site. Hope this information will be useful for your research of HMGN5.
Ywhae
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References
- Zhou, XH; Yuan, B; et al. The expression and clinical significance of high mobility group nucleosome binding domain 5 in human osteosarcoma. TUMOR BIOLOGY 35:6539-6547(2014).
- Yang, CQ; Gao, R; et al. High-mobility group nucleosome-binding domain 5 increases drug resistance in osteosarcoma through upregulating autophagy. TUMOR BIOLOGY 35:6357-6363(2014).
