HIST2H2AA4
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Official Full Name
HIST2H2AA4 histone cluster 2, H2aa4 [ Homo sapiens ] -
Overview
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the telomeric copy. -
Synonyms
histone cluster 2, H2aa4;29668;Ensembl:ENSG00000203812;histone H2A type 2-A;histone H2A/r;histone 2, H2aa4;H2A/R
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| HIST2H2AA4-13800H | Recombinant Human HIST2H2AA4, GST-tagged | E.coli | Human | GST | 1-130a.a. |
Involved Pathway
HIST2H2AA4 involved in several pathways and played different roles in them. We selected most pathways HIST2H2AA4 participated on our site, such as Alcoholism,Systemic lupus erythematosus, which may be useful for your reference. Also, other proteins which involved in the same pathway with HIST2H2AA4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Systemic lupus erythematosus | HIST1H2AM,HIST2H2BB,HIST1H2BH,HIST1H3E,HLA-DPA1,HIST1H4A,HIST1H2BM,HIST1H2BO,HIST1H4D,HIST1H2AO |
| Alcoholism | HIST4H4,SLC6A3,HIST1H2BH,SHC3,HIST1H3A,SLC18A1,GNB4,HDAC6,HIST1H2AD,HIST1H2AA |
Protein Function
HIST2H2AA4 has several biochemical functions, for example, DNA binding,molecular_function,protein heterodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HIST2H2AA4 itself. We selected most functions HIST2H2AA4 had, and list some proteins which have the same functions with HIST2H2AA4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein heterodimerization activity | IKBKG,HIST1H2B5,ANO9A,ZBTB1,PANX1,HOMER2,ADORA1,HIST1H2BO,HIST1H4I,MYOG |
| DNA binding | CHD2,PRDM12,LBX2,HER2,SMTNL,RBM5,MND1,HIST1H2AN,FOXQ2,ZFP628 |
| molecular_function | NPRL3,GLOD5,LRIG2,EMC10,BEST2,CSRP2,RAI2,NCCRP1,MZT2,TMEM170 |
Interacting Protein
HIST2H2AA4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HIST2H2AA4 here. Most of them are supplied by our site. Hope this information will be useful for your research of HIST2H2AA4.
G3BP1;q5ngc7_fratt;AIM2;NS;NS;US11;P/V/C;P/V/C;SPI-2;P/V;GRB2;k7_vaccw;VP35;NS;LRRK2;nsp1_rotp5;GEMIN5;P/V/C;polg_hcvco
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