HIST1H1E
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Official Full Name
histone cluster 1, H1e -
Overview
Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Jul 2008] -
Synonyms
HIST1H1E;histone cluster 1, H1e;H1E;H1.4;H1F4;H1s-4;dJ221C16.5;histone H1.4;histone H1b;histone H1s-4;histone 1, H1e;H1 histone family, member 4
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| HIST1H1E-4775H | Recombinant Human HIST1H1E Protein, GST-tagged | Wheat Germ | Human | GST |
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| HIST1H1E-7646M | Recombinant Mouse HIST1H1E Protein | Mammalian Cell | Mouse | His |
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| HIST1H1E-5551HCL | Recombinant Human HIST1H1E 293 Cell Lysate | HEK293 | Human | Non |
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| HIST1H1E-3566HF | Recombinant Full Length Human HIST1H1E Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 219 amino acids |
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| HIST1H1E-4177M | Recombinant Mouse HIST1H1E Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| HIST1H1E-4177M-B | Recombinant Mouse HIST1H1E Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
HIST1H1E involved in several pathways and played different roles in them. We selected most pathways HIST1H1E participated on our site, such as Activation of DNA fragmentation factor,Apoptosis,Apoptosis induced DNA fragmentation, which may be useful for your reference. Also, other proteins which involved in the same pathway with HIST1H1E were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cellular responses to stress | RBBP4,HBXIP,LAMTOR1,BAG5,DNAJC7,AMBRA1B,RBBP7,TINF2,DPF1,SUZ12A |
| Formation of Senescence-Associated Heterochromatin Foci (SAHF) | ASF1A,EP400,HIST1H1B,HIST1H1C,HIST1H1A,HIST1H1D,HMGA1-RS1,UBN1,HIRA,H1F0 |
| Cellular Senescence | HIRA,TERF1,POT1A,MOV10,KAT5,RAD50,H3F3B.1,POT1,EP400,HIST1H1D |
| Apoptosis | CASP4,SATB1,PRKAR2B,PPP3R1,BAD,DSG3,HIST1H1B,PTBP3,CTNNB1,PRKAR2AB |
| Activation of DNA fragmentation factor | HMGB2A,HMGB2,H1F0,HIST1H1B,HIST1H1A,HIST1H1D,HIST1H1C,DFFA |
| DNA Damage/Telomere Stress Induced Senescence | UBN1,POT1,HIST1H1C,HIST1H1D,ASF1A,HMGA1-RS1,HIRA,TERF2IP,HIST1H1A,HIST1H1B |
| Apoptotic execution phase | SPNA2,HIST1H1D,CASP6L1,ADD1,CTNNB1,OCLN,DNM1L,HIST1H1C,PKP1,PTBP3 |
| Apoptosis induced DNA fragmentation | HMGB2,DFFA,HMGB2A,HIST1H1B,HIST1H1A,HIST1H1C,HIST1H1D,H1F0 |
Protein Function
HIST1H1E has several biochemical functions, for example, chromatin DNA binding,poly(A) RNA binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HIST1H1E itself. We selected most functions HIST1H1E had, and list some proteins which have the same functions with HIST1H1E. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | TTR,DOCK9,USP25,IL10RA,INTS5,BAG1,PLXND1,IER3,KCTD5,STX4A |
| chromatin DNA binding | PPARGC1A,ACTN4,GRHL2,RUVBL2,MYOG,H1F0,RARA,ZIC2,INSM1A,GATA1 |
| poly(A) RNA binding | CSRP1,HIST4H4,MTPAP,HNRNPK,POLDIP3,GLRX3,ZC3H7A,TRAP1,MRPL32,RTCD1 |
Interacting Protein
HIST1H1E has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HIST1H1E here. Most of them are supplied by our site. Hope this information will be useful for your research of HIST1H1E.
L3MBTL1;PPP2R2B;PARP2;NCK1;MAP3K14;pre-let-7a
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