HIP1R
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Official Full Name
huntingtin interacting protein 1 related -
Overview
Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3-phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis. -
Synonyms
HIP1R;huntingtin interacting protein 1 related;HIP3;HIP12;ILWEQ;huntingtin-interacting protein 1-related protein;HIP-12;HIP1-related protein;huntingtin interacting protein 12;huntingtin-interacting protein 12
Recombinant Proteins
- Human
- Chicken
- Mouse
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mamanlian cells
- GST
- His
- Myc&DDK
- His&T7
- Non
- His&Fc&Avi
- Flag
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| HIP1R-13784H | Recombinant Human HIP1R, GST-tagged | E.coli | Human | GST | 266-615a.a. | |
| HIP1R-2363C | Recombinant Chicken HIP1R | Mammalian Cell | Chicken | His |
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| HIP1R-29320TH | Recombinant Human HIP1R, His-tagged | E.coli | Human | His | 729-876 a.a. |
|
| HIP1R-29H | Recombinant Human HIP1R, GST-tagged | Wheat Germ | Human | GST | 1-1068 a.a. |
|
| HIP1R-30H | Recombinant Human HIP1R, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| HIP1R-7635M | Recombinant Mouse HIP1R Protein | Mammalian Cell | Mouse | His |
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| HIP1R-7857H | Recombinant Human HIP1R protein, His & T7-tagged | E.coli | Human | His&T7 | Ser771~Ala1012 |
|
| HIP1R-789HCL | Recombinant Human HIP1R cell lysate | Human | Non |
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| HIP1R-3232H | Recombinant Human HIP1R Protein (Ser771-Ala1012), N-His tagged | E.coli | Human | His | Ser771-Ala1012 |
|
| Hip1r-3399M | Recombinant Mouse Hip1r Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| HIP1R-4168M | Recombinant Mouse HIP1R Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| HIP1R-4168M-B | Recombinant Mouse HIP1R Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| HIP1R-4385H | Recombinant Human HIP1R Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| HIP1R-560HF | Recombinant Full Length Human HIP1R Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 1068 amino acids |
|
| HIP1R-9016HFL | Recombinant Full Length Human HIP1R, Flag-tagged | Mamanlian cells | Human | Flag | Full L. |
|
Involved Pathway
HIP1R involved in several pathways and played different roles in them. We selected most pathways HIP1R participated on our site, such as Clathrin derived vesicle budding,Golgi Associated Vesicle Biogenesis,Membrane Trafficking, which may be useful for your reference. Also, other proteins which involved in the same pathway with HIP1R were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| trans-Golgi Network Vesicle Budding | DTNBP1B,BLOC1S6,PICALM,YIPF6,CPD,TFR1B,FTH1A,CNO,TGOLN2,HIP1RB |
| Membrane Trafficking | MYO6B,GORASP1,FTH1B,EXOC3,TFR1B,COPE,DAB2,NAPAA,AP3S1,CTAGE5 |
| Golgi Associated Vesicle Biogenesis | FTH1A,SH3D19,CNO,TFR1B,PLDN,SNX9A,TBC1D8B,TGOLN2,AP1S3A,SNX9 |
| Clathrin derived vesicle budding | TGOLN2,HIP1RB,AP3S1,AP1G1,CLTB,PICALMA,NECAP1,TBC1D8B,CTSZ,AP1S3A |
| Vesicle-mediated transport | HPX,SH3D19,TRAPPC5,PPP6C,AP4B1,MYO6A,LOC479668,STAB2,HYOU1,TRAPPC2L |
Protein Function
HIP1R has several biochemical functions, for example, actin binding,clathrin binding,phosphatidylinositol binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HIP1R itself. We selected most functions HIP1R had, and list some proteins which have the same functions with HIP1R. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| actin binding | GCET2,FBXO25,MYO3B,PHACTR4,RP2,NF2,ABRAB,PHACTR3,LMOD2,FLII |
| clathrin binding | PICALM,PICALMA,SYT5,SYT15,SYT7,LDLRAP1,CLINT1,AFTPHA,AFTPH,AP2B1 |
| phosphatidylinositol binding | ZCCHC2,SNX9,SNX12,TULP4,SNX5,SNX29,SNX16,SNX6,SNX1,TULP4A |
| protein binding | PRKCE,ACOT8,TGFB1,TDP1,FOXJ2,LRRC26,MLLT3,JUP,HNRNPAB,SNAPIN |
Interacting Protein
HIP1R has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HIP1R here. Most of them are supplied by our site. Hope this information will be useful for your research of HIP1R.
q53hg7_human;UBA1;UBE2N;UBE2V1;Map3k1;pi3p;Sec24c;GAK;CLTB;VCAM1;MYH9;CAPZA2;CD81;Actb
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