HIC2
-
Official Full Name
hypermethylated in cancer 2 -
Overview
Hypermethylated in cancer 2 protein is a protein that in humans is encoded by the HIC2 gene. -
Synonyms
HIC2;hypermethylated in cancer 2;hypermethylated in cancer 2 protein;HRG22;KIAA1020;ZBTB30;ZNF907;HIC1-related gene on chromosome 22;Hic3;Zinc finger and BTB domain-containing protein 30;hic-2;hic-3;HIC1-related gene on chromosome 22 protein
Recombinant Proteins
- Human
- Chicken
- Mouse
- Zebrafish
- E.coli
- Wheat Germ
- Mammalian Cell
- HEK293
- In Vitro Cell Free System
- HIS
- GST
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| HIC2-055H | Recombinant Human HIC2 Protein, HIS-tagged | E.coli | Human | HIS |
|
|
| HIC2-4745H | Recombinant Human HIC2 Protein, GST-tagged | Wheat Germ | Human | GST |
|
|
| HIC2-4878C | Recombinant Chicken HIC2 | Mammalian Cell | Chicken | His |
|
|
| HIC2-4879C | Recombinant Chicken HIC2 | Mammalian Cell | Chicken | His |
|
|
| HIC2-7621M | Recombinant Mouse HIC2 Protein | Mammalian Cell | Mouse | His |
|
|
| HIC2-853H | Recombinant Human HIC2 | Mammalian Cell | Human | His |
|
|
| HIC2-9658Z | Recombinant Zebrafish HIC2 | Mammalian Cell | Zebrafish | His |
|
|
| HIC2-786HCL | Recombinant Human HIC2 cell lysate | Human | Non |
|
||
| HIC2-3109H | Recombinant Human HIC2 Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
|
|
| HIC2-3109H-B | Recombinant Human HIC2 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
|
||
| HIC2-3466HF | Recombinant Full Length Human HIC2 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 615 amino acids |
|
| HIC2-4161M | Recombinant Mouse HIC2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
|
|
| HIC2-4161M-B | Recombinant Mouse HIC2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
|
Involved Pathway
HIC2 involved in several pathways and played different roles in them. We selected most pathways HIC2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with HIC2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
HIC2 has several biochemical functions, for example, DNA binding,metal ion binding,protein C-terminus binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HIC2 itself. We selected most functions HIC2 had, and list some proteins which have the same functions with HIC2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein C-terminus binding | GRIP1,SHANK3,PXK,CLIC6,RAD51,JAK2,YWHAQ,ID1,EFHC1,BLOC1S2A |
| metal ion binding | PPM1E,TIMP2,ZC3H18,ITGA1,SALL1A,FTR67,ZFP90,ITGB2,SMAD1,PPM1L |
| DNA binding | ESR2B,ZNF620,TSHZ3,ZFP879,POLR2A,ZFP354C,HIST2H4A,ZFP639,MNX2A,BANP |
Interacting Protein
HIC2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HIC2 here. Most of them are supplied by our site. Hope this information will be useful for your research of HIC2.
HIC1;PDK2;q2i360_hbv;CDC5L
Resources
Related Services
Related Products
References
- Lv, L; Li, Y; et al. MiR-193a-3p promotes the multi-chemoresistance of bladder cancer by targeting the HOXC9 gene. CANCER LETTERS 357:105-113(2015).
- Lv, L; Deng, H; et al. The DNA methylation-regulated miR-193a-3p dictates the multi-chemoresistance of bladder cancer via repression of SRSF2/PLAU/HIC2 expression. CELL DEATH & DISEASE 5:-(2014).
