HEXIM1
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Official Full Name
hexamethylene bis-acetamide inducible 1 -
Overview
Expression of this gene is induced by hexamethylene-bis-acetamide in vascular smooth muscle cells. This gene has no introns. [provided by RefSeq, Jul 2008] -
Synonyms
HEXIM1;hexamethylene bis-acetamide inducible 1;CLP1;EDG1;HIS1;MAQ1;protein HEXIM1;HMBA-inducible;menage a quatre 1;cardiac lineage protein 1;menage a quatre protein 1;estrogen down-regulated gene 1 protein;hexamthylene bis-acetamide inducible 1;hexamethylene bisacetamide-inducible protein;hexamethylene bis-acetamide-inducible protein 1;hexamethylene-bis-acetamide-inducible transcript 1
Recombinant Proteins
- Rhesus macaque
- Human
- Rat
- Zebrafish
- Mouse
- Mammalian Cell
- E.coli
- Wheat Germ
- Human
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
- His&Fc&Avi
Involved Pathway
HEXIM1 involved in several pathways and played different roles in them. We selected most pathways HEXIM1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with HEXIM1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
HEXIM1 has several biochemical functions, for example, 7SK snRNA binding,cyclin-dependent protein serine/threonine kinase inhibitor activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HEXIM1 itself. We selected most functions HEXIM1 had, and list some proteins which have the same functions with HEXIM1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| snRNA binding | NCBP2,SNRNP35,CCNT1,RBPMS,HEXIM2,CDK9 |
| cyclin-dependent protein serine/threonine kinase inhibitor activity | CDKN1BA,KAT2B,CDKN1C,CDKN1A,CDKN1B,INCA1,CDKN1D,CDKN2C,Casp3,CDKN1BB |
| 7SK snRNA binding | DDX21,HEXIM2 |
| protein binding | AHCY,BANF1,BCAR1,LCMT1,TPI1,CEP104,GNAI2,UBE2D4,HIP1R,WWTR1 |
Interacting Protein
HEXIM1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HEXIM1 here. Most of them are supplied by our site. Hope this information will be useful for your research of HEXIM1.
CDK9;CCNT1;TERF2;LARP7;EGFR
Resources
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References
- Breuer, D; Kotelkin, A; et al. CDK2 Regulates HIV-1 Transcription by Phosphorylation of CDK9 on Serine 90. RETROVIROLOGY 9:-(2012).
- Fujimoto, Y; Nakamura, Y; et al. HEXIM1-binding elements on mRNAs identified through transcriptomic SELEX and computational screening. BIOCHIMIE 94:1900-1909(2012).
- Krueger, BJ; Varzavand, K; et al. The Mechanism of Release of P-TEFb and HEXIM1 from the 7SK snRNP by Viral and Cellular Activators Includes a Conformational Change in 7SK. PLOS ONE 5:-(2010).
- Stone, B; Schummer, M; et al. Serologic analysis of ovarian tumor antigens reveals a bias toward antigens encoded on 17q. INTERNATIONAL JOURNAL OF CANCER 104:73-84(2003).
