HECW2
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Official Full Name
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 -
Synonyms
HECW2;HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2;E3 ubiquitin-protein ligase HECW2;KIAA1301;NEDL2;E3 ubiquitin protein ligase HECW2;KIAA130;NEDD4 like E3 ubiquitin protein ligase 2;NEDD4 Related E3 Ubiquitin Ligase;NEDD4-related E3 ubiquitin ligase NEDL2;NEDD4-like E3 ubiquitin-protein ligase 2;HECT, C2 and WW domain-containing protein 2
Recombinant Proteins
- Human
- Mouse
- Wheat Germ
- Mammalian Cell
- HEK293
- HEK293T
- GST
- His
- Myc&DDK
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| HECW2-4680H | Recombinant Human HECW2 Protein, GST-tagged | Wheat Germ | Human | GST |
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| HECW2-7564M | Recombinant Mouse HECW2 Protein | Mammalian Cell | Mouse | His |
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| HECW2-1100H | Recombinant Human HECW2 Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| Hecw2-3380M | Recombinant Mouse Hecw2 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| HECW2-4115M | Recombinant Mouse HECW2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| HECW2-4115M-B | Recombinant Mouse HECW2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| HECW2-4599H | Recombinant Human HECW2 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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Involved Pathway
HECW2 involved in several pathways and played different roles in them. We selected most pathways HECW2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with HECW2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
HECW2 has several biochemical functions, for example, UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity,coenzyme F420-0 gamma-glutamyl ligase activity,coenzyme F420-2 alpha-glutamyl ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HECW2 itself. We selected most functions HECW2 had, and list some proteins which have the same functions with HECW2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ligase activity | PELI1,RNF216,TRIM32,DTX4,ZNRF2,TRIM69,MUL1,TRIM11,UBE2D1A,BTRC |
| ubiquitin protein ligase activity | UBE2G1B,RNF222,SMURF2,RNF115,RFWD2,RNF6,MED21,RNF4,RNF144B,UBE2B |
| tubulin-glycine ligase activity | UBR1,ZNRF2B,MUL1A,RFWD2,DTX1,ZNRF3,SIAH1A,RNF144AA,UBE2IA,MYLIPB |
| tubulin-glutamic acid ligase activity | MARCH5L,RNF180,RNF144AA,MYLIPA,ITCHA,RNF169,UBE2IB,MUL1A,UBR1,MGRN1A |
| coenzyme F420-2 alpha-glutamyl ligase activity | MARCH5L,HERC2,SIAH1A,RNF169,RNF144AA,RFWD2,TMEM129,RC3H2,MUL1A,SIAH2L |
| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity | ZNRF3,TRIM41,RFWD2,MUL1A,DTX1,HERC2,RNF187,MGRN1A,RNF144AA,MARCH11 |
| ubiquitin-protein transferase activity | TRIM2,RNF139,RNF141,RNF144AA,MALT1,UBA1,PEX2,RNF130,NHLRC1,RNF181 |
| protein-glycine ligase activity, elongating | TRIM50,RNF169,MARCH6,MYLIPB,RNF187,RNF180,RFWD2,ITCHA,RNF144AA,RAG1 |
| coenzyme F420-0 gamma-glutamyl ligase activity | RNF144AA,RNF149,ARIH1L,NEURL1B,SIAH1A,G2E3,MARCH6,MARCH9,SHRPRBCK1R,RNF144AB |
Interacting Protein
HECW2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HECW2 here. Most of them are supplied by our site. Hope this information will be useful for your research of HECW2.
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