HBXIP
-
Official Full Name
hepatitis B virus x interacting protein -
Overview
This gene encodes a protein that specifically complexes with the C-terminus of hepatitis B virus X protein (HBx). The function of this protein is to negatively regulate HBx activity and thus to alter the replication life cycle of the virus. -
Synonyms
HBXIP;hepatitis B virus x interacting protein;hepatitis B virus X-interacting protein;HBx interacting protein;hepatitis B virus x interacting protein (9.6kD);MGC71071;XIP;HBV X interacting protein;HBx-interacting protein;HBV X-interacting protein;hepatitis B virus x-interacting protein (9.6kD)
Recombinant Proteins
- Human
- Chicken
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- GST
- His
- Non
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| HBXIP-13689H | Recombinant Human HBXIP, GST-tagged | E.coli | Human | GST | 1-173a.a. | |
| HBXIP-4063C | Recombinant Chicken HBXIP | Mammalian Cell | Chicken | His |
|
|
| HBXIP-4611H | Recombinant Human HBXIP Protein, GST-tagged | Wheat Germ | Human | GST |
|
|
| HBXIP-6961H | Recombinant Human Hepatitis B Virus X Interacting Protein, His-tagged | E.coli | Human | His | 1-173aa |
|
| HBXIP-5616HCL | Recombinant Human HBXIP 293 Cell Lysate | HEK293 | Human | Non |
|
|
| HBXIP-3022H | Recombinant Human HBXIP protein, GST-tagged | E.coli | Human | GST | 1-91aa |
|
| HBXIP-3501HF | Recombinant Full Length Human HBXIP Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 173 amino acids |
|
Involved Pathway
HBXIP involved in several pathways and played different roles in them. We selected most pathways HBXIP participated on our site, such as Cellular responses to stress,Energy dependent regulation of mTOR by LKB1-AMPK,Gene Expression, which may be useful for your reference. Also, other proteins which involved in the same pathway with HBXIP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Hepatitis B | CASP8,CCND1,CREB3L3,VDAC3,Fasl,IKBKE,PIK3CB,CREB3L1,RELA,KRAS |
| Cellular responses to stress | RPS19BP1,MAP1LC3B,EPAS1B,BMI1A,ULK1A,EGLN3,NUP35,POT1A,SUZ12A,HIRA |
| Generic Transcription Pathway | ZNF136,ZNF445,ZNF334,ZNF776,ZNF713,ZNF786,TEAD1A,FAM36A,TBX5,CDK8 |
| IGF1R signaling cascade | LAMTOR1,RRAGB,IGF2B,EIF4B,RRAGA,C7orf59 |
| Gene Expression | ZNF225,SNAPC3,SPCS3,ZNF2,RBM5,GATAD2AB,AEBP2,ZNF383,RARAA,ZNF791 |
| IRS-related events triggered by IGF1R | IGF2B,RRAGB,RRAGA,LAMTOR1,C7orf59 |
| IRS-mediated signalling | RRAGA,C7orf59,LAMTOR1,RRAGB |
| Energy dependent regulation of mTOR by LKB1-AMPK | RRAGB,LAMTOR1,RRAGA,C7orf59 |
Protein Function
HBXIP has several biochemical functions, for example, contributes_to guanyl-nucleotide exchange factor activity,protein binding,contributes_to protein complex scaffold. Some of the functions are cooperated with other proteins, some of the functions could acted by HBXIP itself. We selected most functions HBXIP had, and list some proteins which have the same functions with HBXIP. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | SPG7,KLHL12,RABL2,HIST1H1E,NKX2,NUAK1,BOLL,LRRC4C,KHDC3,PDS5B |
| contributes_to protein complex scaffold | LAMTOR2,LAMTOR3,C7orf59,LAMTOR1 |
| contributes_to guanyl-nucleotide exchange factor activity | C7orf59,EIF2B5,ALS2,LAMTOR1,EIF2B2,EIF2B3,EIF2B4,LAMTOR2,LAMTOR3,EIF2B1 |
Interacting Protein
HBXIP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HBXIP here. Most of them are supplied by our site. Hope this information will be useful for your research of HBXIP.
LAMTOR4;LAMTOR1;RRAGC;LAMTOR2
Resources
Related Services
Related Products
References
- Cheng, DY; Liang, B; et al. HBXIP expression predicts patient prognosis in breast cancer. MEDICAL ONCOLOGY 31:-(2014).
- Li, YH; Zhang, Z; et al. The oncoprotein HBXIP enhances migration of breast cancer cells through increasing filopodia formation involving MEKK2/ERK1/2/Capn4 signaling. CANCER LETTERS 355:288-296(2014).
