H2-EA-PS
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Official Full Name
histocompatibility 2, class II antigen E alpha, pseudogene -
Overview
This locus belongs to the class II major histocompatibility complex (MHC) family of genes, which encode immune response (Ia) antigens that function in the T-cell-dependent immune response. This family member has multiple haplotypes, some of which result in the production of an E-alpha subunit that combines with an E-beta subunit to form a functional E complex at the cell surface. Other haplotypes, including that of the reference genome allele, contain mutations and they thus represent polymorphic pseudogenes that do not produce functional products. These mutations include frameshifting indels, nonsense mutations, and deletions of larger regions. The reference genome haplotype contains a deletion at the 5 end of the gene, including the core promoter region and the transcription start site, and therefore no transcripts result from this haplotype. -
Synonyms
H2-EA-PS;histocompatibility 2, class II antigen E alpha, pseudogene;AI323765;E alpha f;H 2 class II histocompatibility antigen E D alpha chain;H 2Ea;H2 class II histocompatibility antigen E D alpha chain;H2 Ea;H2 Ea histocompatibility 2 class II antigen E alpha;H2 IE alpha;H2Ea;Histocompatibility 2 class II antigen E alpha;I E alpha MHC class II;Ia 3;Ia3;Major histocompatibility complex H 2E alpha chain;MGC117888;MHC class II antigen E alpha;Ia-3;H-2Ea;H2-Ea;I-Ealpha;E-alpha-f
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Involved Pathway
H2-EA-PS involved in several pathways and played different roles in them. We selected most pathways H2-EA-PS participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with H2-EA-PS were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
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Protein Function
H2-EA-PS has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by H2-EA-PS itself. We selected most functions H2-EA-PS had, and list some proteins which have the same functions with H2-EA-PS. You can find most of the proteins on our site.
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Interacting Protein
H2-EA-PS has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with H2-EA-PS here. Most of them are supplied by our site. Hope this information will be useful for your research of H2-EA-PS.
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