H2-AB1

  • Official Full Name

    histocompatibility 2, class II antigen A, beta 1
  • Synonyms

    H2-AB1;histocompatibility 2, class II antigen A, beta 1;Abeta;AI845868;H2 Ab;H2 Ab1;H2 I A beta;Histocompatibility 2 class II antigen A beta 1;Ia2;Iab;MHC class II antigen I A beta 1;Rmcs1;OTTMUSP00000053328;MHC class II H2-IA-beta-psi;MHC class II antigen A beta;response to metastatic cancers 1;major histocompatibility complex class II beta chain;H-2 class II histocompatibility antigen, A be;Ia-2;H-2Ab;H2-Ab;I-Abeta
Cat.# Product name Source (Host) Species Tag Protein Length Price
H2-AB1-7425M Recombinant Mouse H2-AB1 Protein Mammalian Cell Mouse His
H2-AB1-4039M Recombinant Mouse H2-AB1 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
H2-AB1-4039M-B Recombinant Mouse H2-AB1 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    H2-AB1 involved in several pathways and played different roles in them. We selected most pathways H2-AB1 participated on our site, such as Phagosome,Cell adhesion molecules (CAMs),Antigen processing and presentation, which may be useful for your reference. Also, other proteins which involved in the same pathway with H2-AB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Allograft rejection FASLG,HLA-DRB5,H2-AA,HLA-DRA,IFNG,HLA-DQB1,Il2,HLA-DQA2,PRF1,Fasl
    Intestinal i CD40LG,ITGA4,CXCR4A,IL15,ITGB7,BMA2,CCR9A,CCL27B,TNFSF13,MHC2DEB
    Systemic lupus erythematosus GM14479,IFNG,HIST1H3I,HIST1H2AP,HIST1H3G,ACTN2,C8A,C5,CD86,HIST2H2BB
    Staphylococcus aureus infection FPR1,ITGAL,HLA-DRB3,C1R,CFB,C5AR1,HLA-DPB1,HLA-DQB1,C1QA,HLA-DRB4
    Rheumatoid arthritis Il23a,CCL5,TLR4,HLA-DOB,Il23a; Il12b,IL15,HLA-DRB5,CXCL12,ATP6V0B,ATP6AP1
    Inflammatory bowel disease (IBD) RORC,IL21R,TLR2,HLA-DQB1,NFKB1,TLR4,HLA-DRB3,IL1A,IL21,TGFB3
    Leishmaniasis IL1A,TRAF6,HLA-DRB3,RELA,TGFB3,MYD88,FCGR1,HLA-DRA,HLA-DQB1,HLA-DMB
    Cell adhesion molecules (CAMs) NLGN2,NRCAM,HLA-E,CD22,ICAM2,CDH1,NLGN4X,CNTNAP2A,CLDN11B,HLA-DOA
    Herpes simplex infection IKBKG,SRSF5A,SRSF2,PKZ,MED8,Ccl12,TNFRSF14,HLA-F,C5,IFNA8

    Protein Function

    H2-AB1 has several biochemical functions, for example, peptide antigen binding,protein antigen binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by H2-AB1 itself. We selected most functions H2-AB1 had, and list some proteins which have the same functions with H2-AB1. You can find most of the proteins on our site.

    Function Related Protein
    transcription factor binding IFT172,PPID,TCF12,KCNA3,ARNT,HYAL1,KCTD1,EPAS1,DOT1L,PBX1
    peptide antigen binding HLA-DPB1,HLA-F,MHC1ZE,MHC1UHA,TAPBP,MHC1ZKA,MHC1UJA,MHC1UFA,TRGV3,HLA-B
    protein antigen binding KLRC2,KLRD1,EP300,ITGA4
    ubiquitin protein ligase binding SNCAIP,ERLIN2,TCEB2,SQSTM1,SMAD5,HSPA1B,PDE4D,UBE2J1,XBP1,SLC25A5
    toxic substance binding Alb,PHAX,DSG1,NEFH,AZU1,ASS1,CHRNA7,A4GALT,GUCY2C,EPHX2
    protein heterodimerization activity SOX14,PDX1,PVALB,ENO3,KATNB1,H2AFVB,Bcl2a1b,HGF,UBA2,TTR
    protein binding RTN2,RAI2,MAP4K5,PTPMT1,VLDLR,EPB41L3,TMEM31,GRAP,MSH5,RALGAPA1

    Interacting Protein

    H2-AB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with H2-AB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of H2-AB1.

    H2-Aa

    Resources

    References

    • Zemelka-Wiacek, M; Szczepanik, M; et al. Tc1-mediated contact sensitivity reaction, its mechanism and regulation. POSTEPY HIGIENY I MEDYCYNY DOSWIADCZALNEJ 68:955-969(2014).
    • Frigstad, T; Loset, GA; et al. A Public T cell Receptor Recognized by a Monoclonal Antibody Specific for the D-J Junction of the beta-chain. SCANDINAVIAN JOURNAL OF IMMUNOLOGY 78:345-351(2013).

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