Gabra6
-
Official Full Name
gamma-aminobutyric acid (GABA) A receptor, alpha 6 -
Overview
GABAA receptor subunit; part of a cerebellar receptor subtype, selective for antagonist of alcohol-induced motor incoordination and ataxia -
Synonyms
GABRA6;gamma-aminobutyric acid (GABA) A receptor, alpha 6;gamma-aminobutyric acid receptor subunit alpha-6;GABA A;GABA A Receptor alpha 6polypeptide;GABA A receptor alpha 6;GABA A receptor subunit alpha 6;GABA subunit A receptor alpha 6;GABA(A) receptor subunit alpha-6;GABRA 6;Gamma aminobutyric acid A receptor alpha 6;Gamma aminobutyric acid GABA A receptor alpha 6;Gamma aminobutyric acid receptor subunit alpha 6;GBRA6_HUMAN;MGC116903;MGC116904;GABA-A receptor alpha-6 subunit;gamma-aminobutyric acid A receptor, alpha 6;gamma-aminobutyric acidA receptor, alpha 6;gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 6
Recombinant Proteins
- Human
- Rat
- Mouse
- Chicken
- E.coli
- Mammalian Cell
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- His&Fc&Avi
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| GABRA6-13096H | Recombinant Human GABRA6, His-tagged | E.coli | Human | His | 329-424a.a. | |
| GABRA6-2447R | Recombinant Rat GABRA6 Protein | Mammalian Cell | Rat | His |
|
|
| GABRA6-6148M | Recombinant Mouse GABRA6 Protein | Mammalian Cell | Mouse | His |
|
|
| GABRA6-6615C | Recombinant Chicken GABRA6 | Mammalian Cell | Chicken | His |
|
|
| GABRA6-1546H | Recombinant Human GABRA6 Protein, His-tagged | E.coli | Human | His | Glu41-Gln207 |
|
| Gabra6-1547M | Recombinant Mouse Gabra6 Protein, His-tagged | E.coli | Mouse | His | Gln20-Tyr242 |
|
| GABRA6-2103R | Recombinant Rat GABRA6 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
|
|
| GABRA6-2103R-B | Recombinant Rat GABRA6 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
|
||
| GABRA6-3429M | Recombinant Mouse GABRA6 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
|
|
| GABRA6-3429M-B | Recombinant Mouse GABRA6 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
|
||
| GABRA6-4643H | Recombinant Human GABRA6 Protein, GST-tagged | Wheat Germ | Human | GST |
|
|
| GABRA6-5194HF | Recombinant Full Length Human GABRA6 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 453 amino acids |
|
Involved Pathway
Gabra6 involved in several pathways and played different roles in them. We selected most pathways Gabra6 participated on our site, such as Neuroactive ligand-receptor interaction,Retrograde endocannabinoid signaling,GABAergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with Gabra6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Nicotine addiction | GRIA1,GRIA4,GRIN1,SLC17A7,GABRE,GABRB2,GABRR3,GABRD,GRIN3B,GABRR2 |
| Retrograde endocannabinoid signaling | GABRR1,GABRA4,SLC17A7,GNG8,GNGT1,GABRR2,GABRA2,PRKCB,MAPK9,MAPK3 |
| Neuroactive ligand-receptor interaction | GABRA3,TSHR,HTR1B,BDKRB2,S1PR5,GABRA4,MC3R,IL12,DRD4B,P2RX3 |
| GABAergic synapse | PRKACG,GABBR2,GABRB3,GABARAPL1,GNG10,SLC38A5,GNG3,SLC6A1,GNG7,NSF |
Protein Function
Gabra6 has several biochemical functions, for example, contributes_to GABA-A receptor activity,benzodiazepine receptor activity,chloride channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Gabra6 itself. We selected most functions Gabra6 had, and list some proteins which have the same functions with Gabra6. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| chloride channel activity | CLIC5,SLC26A4,SLC26A7,GABRG2,FXYD3,GABRB2,TTYH3,SLC26A11,CFTR,TTYH2 |
| inhibitory extracellular ligand-gated ion channel activity | GABRA6A,GABRA5,GABRA1,GABRG1,GABRB2,GABRA3,GABRA4,GABRA2,GABRG3,GABRE |
| benzodiazepine receptor activity | GABRA4,GABRA3,TSPO,GABRG2,GABRA2 |
| contributes_to GABA-A receptor activity | GABRA6A,GABRP,GABRG1,GABRA3,GABRG3,GABRA4,GABRG2,GABRA2,GABRZ,GABRA5 |
Interacting Protein
Gabra6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Gabra6 here. Most of them are supplied by our site. Hope this information will be useful for your research of Gabra6.
Resources
Related Services
Related Products
References
- Ament, SA; Szelinger, S; et al. Rare variants in neuronal excitability genes influence risk for bipolar disorder. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 112:3576-3581(2015).
- Srivastava, S; Cohen, J; et al. A Novel Variant in GABRB2 Associated with Intellectual Disability and Epilepsy. AMERICAN JOURNAL OF MEDICAL GENETICS PART A 164A:2914-2921(2014).
