GUCY1A2
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Official Full Name
guanylate cyclase 1, soluble, alpha 2 -
Overview
Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3,5-cyclic GMP and;pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta;subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Two transcript variants encoding;different isoforms have been found for this gene. -
Synonyms
GUCY1A2;guanylate cyclase 1, soluble, alpha 2;GUC1A2;guanylate cyclase soluble subunit alpha-2;GC SA2;GCS-alpha-2;GC-SA2
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| GUCY1A2-2754R | Recombinant Rat GUCY1A2 Protein | Mammalian Cell | Rat | His |
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| GUCY1A2-4488H | Recombinant Human GUCY1A2 Protein, GST-tagged | Wheat Germ | Human | GST |
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| GUCY1A2-1490H | Recombinant Human GUCY1A2 protein, His-tagged | E.coli | Human | His | 500-732aa |
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| GUCY1A2-2408R | Recombinant Rat GUCY1A2 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| GUCY1A2-2408R-B | Recombinant Rat GUCY1A2 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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Involved Pathway
GUCY1A2 involved in several pathways and played different roles in them. We selected most pathways GUCY1A2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with GUCY1A2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
GUCY1A2 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by GUCY1A2 itself. We selected most functions GUCY1A2 had, and list some proteins which have the same functions with GUCY1A2. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
GUCY1A2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GUCY1A2 here. Most of them are supplied by our site. Hope this information will be useful for your research of GUCY1A2.
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References
- Fusco, DN; Brisac, C; et al. A Genetic Screen Identifies Interferon-alpha Effector Genes Required to Suppress Hepatitis C Virus Replication. GASTROENTEROLOGY 144:1438-U210(2013).
- Priora, R; Margaritis, A; et al. In vitro inhibition of human and rat platelets by NO donors, nitrosoglutathione, sodium nitroprusside and SIN-1, through activation of cGMP-independent pathways. PHARMACOLOGICAL RESEARCH 64:289-297(2011).
