GTPBP3
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Official Full Name
GTP binding protein 3 (mitochondrial) -
Overview
This locus encodes a GTP-binding protein. The encoded protein is localized to the mitochondria and may play a role in mitochondrial tRNA modification. Polymorphisms at this locus may be associated with severity of aminoglycoside-induced deafness, a disease associated with a mutation in the 12S rRNA. Alternatively spliced transcript variants encoding different isoforms have been described. -
Synonyms
GTPBP3;GTP binding protein 3 (mitochondrial);tRNA modification GTPase GTPBP3, mitochondrial;FLJ14700;GTPBG3;MSS1;MTGP1;THDF1;GTP binding protein 3;GTP binding protein 3 mitochondrial;GTPBG 3;GTPBP 3;Mitochondrial GTP binding protein 1;Mitochondrial GTP binding protein;MSS 1;MTGP 1;THDF 1;tRNA modification GTPase GTPBP3;tRNA modification GTPase GTPBP3 mitochondrial;mitochondrial GTP-binding protein 1
Recombinant Proteins
- Rat
- Zebrafish
- Human
- Mouse
- Mammalian Cell
- Wheat Germ
- HEK293
- HEK293T
- In Vitro Cell Free System
- His
- GST
- Non
- His&Fc&Avi
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| GTPBP3-2750R | Recombinant Rat GTPBP3 Protein | Mammalian Cell | Rat | His |
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| GTPBP3-2909Z | Recombinant Zebrafish GTPBP3 | Mammalian Cell | Zebrafish | His |
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| GTPBP3-4472H | Recombinant Human GTPBP3 Protein, GST-tagged | Wheat Germ | Human | GST |
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| GTPBP3-5685HCL | Recombinant Human GTPBP3 293 Cell Lysate | HEK293 | Human | Non |
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| GTPBP3-2404R | Recombinant Rat GTPBP3 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| GTPBP3-2404R-B | Recombinant Rat GTPBP3 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| GTPBP3-299H | Recombinant Human GTPBP3 Protein, MYC/DDK-tagged, C13 and N15-labeled | HEK293 | Human | Myc&DDK |
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| Gtpbp3-3333M | Recombinant Mouse Gtpbp3 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| GTPBP3-3424HF | Recombinant Full Length Human GTPBP3 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 492 amino acids |
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Involved Pathway
GTPBP3 involved in several pathways and played different roles in them. We selected most pathways GTPBP3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with GTPBP3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
GTPBP3 has several biochemical functions, for example, GTP binding,GTPase activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GTPBP3 itself. We selected most functions GTPBP3 had, and list some proteins which have the same functions with GTPBP3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| GTP binding | RAB41,RAB6C,RAP2AB,EEF2A.2,OPA1,GIMAP6,RAC1A,ANXA6,RHOF,GMPPB |
| protein binding | IL17RA,PEX11A,CNOT2,KLHDC5,RYR2,NSF,DERL1,VBP1,TAF13,PSMB2 |
| GTPase activity | RAB27B,RAB11BB,RAB3DB,RAB14,RAB40C,TUBA8,EEF1A1B,GNL3L,RAB1,RAB34 |
Interacting Protein
GTPBP3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GTPBP3 here. Most of them are supplied by our site. Hope this information will be useful for your research of GTPBP3.
PFKL;GNE;PRPF3;PTAFR;DCAF8;CIC;RIBC2;FAM60A;PARP11;IGHA1
Resources
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References
- Knorr, M; Hausding, M; et al. Nitroglycerin-Induced Endothelial Dysfunction and Tolerance Involve Adverse Phosphorylation and S-Glutathionylation of Endothelial Nitric Oxide Synthase Beneficial Effects of Therapy With the AT(1) Receptor Blocker Telmisartan. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 31:2223-U187(2011).
- Kim, HR; Chae, HJ; et al. Mammalian dap3 is an essential gene required for mitochondrial homeostasis in vivo and contributing to the extrinsic pathway for apoptosis. FASEB JOURNAL 21:188-196(2007).
- HAMASUR, B; GLASER, E; et al. PLANT MITOCHONDRIAL F0F1 ATP SYNTHASE - IDENTIFICATION OF THE INDIVIDUAL SUBUNITS AND PROPERTIES OF THE PURIFIED SPINACH LEAF MITOCHONDRIAL ATP SYNTHASE. EUROPEAN JOURNAL OF BIOCHEMISTRY 205:409-416(1992).
- RODRIGUEZROSALES, MP; HERRIN, DL; et al. IDENTIFICATION OF LOW-MOLECULAR MASS GTP-BINDING PROTEINS IN MEMBRANES OF THE HALOTOLERANT ALGA DUNALIELLA-SALINA. PLANT PHYSIOLOGY 98:446-451(1992).
